Protein Alignment mAChR-A and LOC100334962

DIOPT Version :9

• Sequence 1: NP_523844.2
• Gene: mAChR-A / 37892
• FlyBaseID: FBgn0000037
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: XP_003200969.1
• Gene: LOC100334962 / 100334962
• -ID: -
• Length: 455
• Species: Danio rerio
• Alignment Length: 769
• Identity: 161/769 - (20%)
• Similarity: 260/769 - (33%)
• Gaps: 342/769 - (44%)

  Fly    34 TTTTSTTTTTAS-----PAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFE 93
            |..:|:....||     |...||.....|::|..     :|:.|              |||....
Zfish     3 TLLSSSAAGKASHDDFRPVAASPNVLDLTMVTCF-----NTSGS--------------NGTTVSP 48

  Fly    94 TKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISM 158
            .:.| :...:||::..:.|.|..|.|.||.:|:::|.:||.|:...|||..:|||:||.:||..:
Zfish    49 AEAP-FPGYTMVILAILMATLVVVVVVGNALVILAFVVDKSLRNQCNYFFLNLAISDFLVGAFCI 112

  Fly   159 PLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAV 223
            ||:....:.|.|.||..:|..||.:|||...|||.|:::||:||:.||||.:.|||::...|.||
Zfish   113 PLYMPYILTGRWMLGRGLCKLWLVMDYLLCTASVFNIVLISYDRFLSVTRAVRYRAQQGVTRLAV 177

  Fly   224 M-IGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAA----FYFPVTI 283
            : :.|.|..:.||:.|.|..|..:.|:..||:|||:.:|     |.|:...|:|    |:.|...
Zfish   178 LKMLAVWVSAFLLYGPAIIFWELLVGESIVPEDECFAEF-----YCTWYFLLSASTFEFFSPFIS 237

  Fly   284 MCFLYWRIWRETKKRQKD-LPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWR 347
            :.|..:.|:...::|.:. :.:::|.|:|.                                 ||
Zfish   238 VAFFNFSIYLNIQRRNRSRMAHVEAEKEDG---------------------------------WR 269

  Fly   348 RPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDS 412
                              |||       .:.||:....|.|.|
Zfish   270 ------------------VID-------GQTSSVFFVKTRKVS---------------------- 287

  Fly   413 DDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTP 477
                  ..||                ::||.     |:.|:                 .:|||
Zfish   288 ------SSEP----------------AAVSA-----VIEDD-----------------EEVSP-- 306

  Fly   478 LPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGT 542
                                      ::||:
Zfish   307 --------------------------SSSGD---------------------------------- 311

  Fly   543 TGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQ 607
             .::||..|.|:.  ..|..|.:....|.|.:||                          :..:.
Zfish   312 -PSSTHSVSLTMK--TTIKKRGLFGGWVRTRIIR--------------------------AQEVT 347

  Fly   608 GDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIP 672
            ..|||.
Zfish   348 NPCAPC----------------------------------------------------------- 353

  Fly   673 KQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILV 737
                ::||          ||.::               ::.|.||:|:.|:..|.:.|.||.:|:
Zfish   354 ----RSGG----------HARLS---------------RDKKIAKSLAVIVCVFGVCWAPYTLLM 389

  Fly   738 LIKPLTTCS-DCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCK 790
            :|:  ..|| .|:....::..:.|.::||.|||..|.||:::|||.:.:||..|
Zfish   390 IIR--AACSGSCVEHHWYEVTFWLLWLNSAINPFLYPLCHSSFRRAFAKILCPK 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-A	NP_523844.2	7tm_4	117..>241	CDD:304433	54/124 (44%)
		7tm_1	121..>314	CDD:278431	73/198 (37%)
LOC100334962	XP_003200969.1	7tm_1	75..423	CDD:278431	131/657 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010