DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bs and mef-2

DIOPT Version :9

Sequence 1:	NP_001286837.1	Gene:	bs / 37890	FlyBaseID:	FBgn0004101	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_492441.1	Gene:	mef-2 / 172732	WormBaseID:	WBGene00003182	Length:	340	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	62/250 - (24%)
Similarity:	107/250 - (42%)	Gaps:	54/250 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GRVKIKMEYIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVMLLVASETGHVYTFATRKLQPMI 230
            ||.||::..|.::..|..||:|||.|:||||||||.|...::.|:|.:.|..::.:|:..:..::
Worm     2 GRKKIQITRIQDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIVFNSTNKLFQYASTDMDKVL 66

  Fly   231 TSEAGKQLIQTCLNSPDPPSVGGGDQRMSATGFEETELSYNIADEDSKDDRSPTSSGNESDDSSD 295
                   |..|..|.|                 .|:..:.:|.:..::.:      ||:...:||
Worm    67 -------LKYTEYNEP-----------------HESRTNNDIMEALNRKE------GNQGGGNSD 101

  Fly   296 VEMPAEAAE--VATKLPA----SKTEVSAPPAASCSAATASSGHKTMPALNYQTDTNSGPSTSTA 354
            .|.|..:..  :...:||    ..:..|...|||.|||..::....:.|:.   .|:||.:.:.|
Worm   102 DESPGPSTSPVIQITMPAVVNGHSSNNSVASAASASAAAVAAAAAAVAAVE---GTSSGAAAAAA 163

  Fly   355 AGGGGSADSKYVYSAASIANIPQKMLRQLIQSGHLQVHAEEDGNQYVTIPLSSTA 409
            |....:|...:      ..|:.|.::.....:.||....:         |||||:
Worm   164 ALQASNAQRHH------NLNLYQNLIFNPNYTRHLNQRND---------PLSSTS 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bs	NP_001286837.1	MADS_SRF_like	166..247	CDD:238166	28/80 (35%)
mef-2	NP_492441.1	MADS_MEF2_like	2..78	CDD:238165	29/99 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5068
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810