DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slbo and Cebpd

DIOPT Version :9

Sequence 1:	NP_001286836.1	Gene:	slbo / 37889	FlyBaseID:	FBgn0005638	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_037286.1	Gene:	Cebpd / 25695	RGDID:	2328	Length:	268	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	71/269 - (26%)
Similarity:	107/269 - (39%)	Gaps:	76/269 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 GRGGGGGAGGALAYMPQPVHATYNNSSDENSSVGSDSSTI-----KEEPIDPEYRRHLQEAASQQ 251
            ||.|..|.|      |:|            ..:|...||.     .|..||  :..::...|:..
  Rat    28 GRVGKPGRG------PEP------------GDLGEPGSTTPAMYDDESAID--FSAYIDSMAAVP 72

  Fly   252 AAFMGNG---AGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGS----------NGSTGSSNGSQF 303
            ...:.:.   |.|:|.....|.  .|....|.||.|.|...||          :...|.:.||
  Rat    73 TLELCHDEIFADLFNSNHKAAG--AGSLELLQGGPTRPPGVGSIARGPLKREPDWGDGDAPGS-- 133

  Fly   304 TNLTTANV-LAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHR--------------K 353
              |..|.| :....:..|||||                |.......:..|              |
  Rat   134 --LLPAQVAVCAQTVVSLAAAA----------------QPTPPTSPEPPRGSPGPSLAPGPVREK 180

  Fly   354 HSNKH-VDKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQ 417
            .:.|. .|:|:.|||:|||||||||||||:|||.|::|:::::..|..|.:.|.:::.::|.:|.
  Rat   181 GAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLA 245

  Fly   418 LHKQIYMQL 426
            ..:|.:.:|
  Rat   246 SLRQFFKEL 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slbo	NP_001286836.1	bZIP_CEBP	362..420	CDD:269841	27/57 (47%)
slbo	NP_001286836.1	coiled coil	363..420	CDD:269841	26/56 (46%)
Cebpd	NP_037286.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50		10/39 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	98..132		8/33 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..223		29/86 (34%)
		bZIP_CEBPD	188..252	CDD:269862	29/63 (46%)
		coiled coil	191..249	CDD:269862	26/57 (46%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	195..222		19/26 (73%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	226..254		6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339750
Domainoid	1	1.000	57	1.000	Domainoid score	I10594
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45708
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23334
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930