Protein Alignment slbo and Nfil3

DIOPT Version :10

• Sequence 1: NP_523843.1
• Gene: slbo / 37889
• FlyBaseID: FBgn0005638
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_059069.1
• Gene: Nfil3 / 18030
• MGIID: 109495
• Length: 462
• Species: Mus musculus
• Alignment Length: 175
• Identity: 37/175 - (21%)
• Similarity: 69/175 - (39%)
• Gaps: 43/175 - (24%)

  Fly   295 TGSSNGSQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHRKHSNKHV 359
            |.||:.....|...|.|...       .|:|...||.:.|.       .:::.....||......
Mouse    19 TSSSDKMLLLNSALAEVAED-------LASGEDLLLNEGSM-------GKNKSSACRRKREFIPD 69

  Fly   360 DKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSL-------------LKEKDALI----- 406
            :|....|..:|.:||.|.::||||.::....:|.::.:|             ||.|..||
Mouse    70 EKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTAY 134

  Fly   407 -RQLGEMTNELQLHKQIYMQLMNHANPEVSRVC-RSFLNTNEHSL 449
             :::.:::|...::.|.|         :.|:.. .||::.:|.::
Mouse   135 AQEIQKLSNSTAVYFQDY---------QTSKAAVSSFVDEHEPAM 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slbo	NP_523843.1	bZIP_CEBP	362..420	CDD:269841	17/76 (22%)
		coiled coil	363..420	CDD:269841	17/75 (23%)
Nfil3	NP_059069.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		1/2 (50%)
		bZIP_NFIL3	72..131	CDD:269842	16/58 (28%)
		coiled coil	73..131	CDD:269842	16/57 (28%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	79..95		8/15 (53%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	99..106		1/6 (17%)
		Vert_IL3-reg_TF	130..461	CDD:368956	7/50 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..214
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..298
		Necessary for transcriptional repression and sufficient for interaction with PER2. /evidence=ECO:0000269|PubMed:17274955	281..420