DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slbo and Cebpd

DIOPT Version :9

Sequence 1:	NP_001286836.1	Gene:	slbo / 37889	FlyBaseID:	FBgn0005638	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_031705.3	Gene:	Cebpd / 12609	MGIID:	103573	Length:	268	Species:	Mus musculus

Alignment Length:	194	Identity:	58/194 - (29%)
Similarity:	86/194 - (44%)	Gaps:	48/194 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 AGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGS----------NGSTGSSNGSQFTNLTTANV-L 312
            |.|:|.....|.  .||...|.||.|.|...||          :...|.:.||    |..|.| :
Mouse    83 ADLFNSNHKAAG--AGGLELLQGGPTRPPGVGSVARGPLKREPDWGDGDAPGS----LLPAQVAV 141

  Fly   313 AHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHR--------------KHSNKH-VDKG 362
            ....:..|||||                |.......:..|              |.:.|. .|:|
Mouse   142 CAQTVVSLAAAA----------------QPTPPTSPEPPRGSPGPSLAPGTVREKGAGKRGPDRG 190

  Fly   363 TDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQLHKQIYMQL 426
            :.|||:|||||||||||||:|||.|::|:::::..|..|.:.|.:::.::|.:|...:|.:.:|
Mouse   191 SPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKKL 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slbo	NP_001286836.1	bZIP_CEBP	362..420	CDD:269841	27/57 (47%)
slbo	NP_001286836.1	coiled coil	363..420	CDD:269841	26/56 (46%)
Cebpd	NP_031705.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..132		9/34 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..219		28/82 (34%)
		bZIP_CEBPD	188..252	CDD:269862	29/63 (46%)
		coiled coil	191..249	CDD:269862	26/57 (46%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	195..222		19/26 (73%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	226..254		6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836086
Domainoid	1	1.000	57	1.000	Domainoid score	I10807
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43632
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23334
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4506
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060