DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slbo and Nfil3

DIOPT Version :9

Sequence 1:	NP_001286836.1	Gene:	slbo / 37889	FlyBaseID:	FBgn0005638	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_446179.2	Gene:	Nfil3 / 114519	RGDID:	620972	Length:	462	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	41/179 - (22%)
Similarity:	70/179 - (39%)	Gaps:	40/179 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 TGSSNGSQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHRKHSNKHV 359
            ||||:.....|...|.|...       .|:|...||.:.|.       .:::.....||......
  Rat    19 TGSSDKMLLLNSALAEVAED-------LASGEDLLLNEGSM-------GKNKSSACRRKREFIPD 69

  Fly   360 DKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSL-------------LKEKDALI----- 406
            :|....|..:|.:||.|.::||||.::....:|.::.:|             ||.|..||
  Rat    70 EKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTVY 134

  Fly   407 -RQLGEMTNELQLHKQIYMQLMNHA------NPEVSRVCRSFLNTNEHS 448
             :::.:::|...::.|.| |....|      ..|.:.|..|.::..:||
  Rat   135 AQEIQKLSNSTAVYFQDY-QTSKAAVSSYVDEHEPAMVAGSCISVIKHS 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slbo	NP_001286836.1	bZIP_CEBP	362..420	CDD:269841	17/76 (22%)
slbo	NP_001286836.1	coiled coil	363..420	CDD:269841	17/75 (23%)
Nfil3	NP_446179.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		2/2 (100%)
		bZIP_NFIL3	72..131	CDD:269842	16/58 (28%)
		coiled coil	76..127	CDD:269842	14/50 (28%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	79..95		8/15 (53%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	99..106		1/6 (17%)
		Vert_IL3-reg_TF	130..461	CDD:368956	10/54 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..214
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..298
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900