Protein Alignment betaTub60D and TUBA1C

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 178/455 - (39%)
• Similarity: 272/455 - (59%)
• Gaps: 22/455 - (4%)

  Fly     2 REIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIY-----VGDSDLQLERVSVYYNEASAVTRSS 61
            ||.:::..||.|.|||...||:...||||..:|..     :|..|   :..:.:::|..|
Human    72 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGD---DSFNTFFSETGA----- 128

  Fly    62 GGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVV 126
             ||:||||:.:||||..::.||:|.|.|||.|:..:.|:..|.||:|:||||.|.|::|.|||.:
Human   129 -GKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRI 192

  Fly   127 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNA 191
            ||..:.|..||||.:.||.|||||||..:||:.::..:|..:....:|:.|:|:||..||||||:
Human   193 RKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNS 257

  Fly   192 TLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADL 256
            .|:.|..:|::|..:.:||||:||||.|.|.:..|:|.:||.|:|..:|.:|..|||.|.||.||
Human   258 ILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDL 322

  Fly   257 RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 321
            .:...|:||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||||:|:....
Human   323 TEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCL 387

  Fly   322 VFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPP--------KGLKMSSTFIGNTT 378
            ::||.:..|:|:..:..::.|.:..||:|.|...|..:...||        ..::.:...:.|||
Human   388 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTT 452

  Fly   379 AIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPE 443
            |:.|.:.|:..:|..|:.::||:|||.||||:|.||:||..:|..|..:|::....:||.|.:.|
Human   453 AVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGE 517

  Fly   444  443
            Human   518  517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	178/455 (39%)
		beta_tubulin	2..432	CDD:276956	174/442 (39%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	178/455 (39%)
		alpha_tubulin	72..505	CDD:276955	174/441 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810