DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub60D and TUB1

DIOPT Version :9

Sequence 1:	NP_523842.2	Gene:	betaTub60D / 37888	FlyBaseID:	FBgn0003888	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_177706.1	Gene:	TUB1 / 843911	AraportID:	AT1G75780	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	363/449 - (80%)
Similarity:	410/449 - (91%)	Gaps:	9/449 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDS-DLQLERVSVYYNEASAVTRSSGGK 64
            ||||:::|.||||||||:||||:|.:|||:|..|.|.||| ||||||::||||||      |||:
plant     1 MREILHVQGGQCGNQIGSKFWEVICDEHGVDPTGRYNGDSADLQLERINVYYNEA------SGGR 59

  Fly    65 YVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKE 129
            |||||:|:|||||||:|:|||||||:|||||||:||||||||||||||||||||:|.||||||||
plant    60 YVPRAVLMDLEPGTMDSIRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKE 124

  Fly   130 CENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLS 194
            .||||||||||:.||||||||||||||||||||||||||:|.|:||.||||||||||||||||||
plant   125 AENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLS 189

  Fly   195 IHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKL 259
            :||||||.||...:||||||||||||||:|.||:||||||:|.||||||..||||||||:|||||
plant   190 VHQLVENADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKL 254

  Fly   260 AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFR 324
            |||::|||||||||.|||||||||||||.:||||||||||:||||||.|.|||||||||.:|:||
plant   255 AVNLIPFPRLHFFMVGFAPLTSRGSQQYISLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFR 319

  Fly   325 GRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISE 389
            |:||.||||||:|.||||||||||||||||||::||||||.|:||:|||:||:|:|||:|:|:||
plant   320 GKMSTKEVDEQILNVQNKNSSYFVEWIPNNVKSSVCDIPPTGIKMASTFVGNSTSIQEMFRRVSE 384

  Fly   390 QFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATAD--DEFDPEVNQ 446
            ||:||||||||||||||||||||||||||||||||||||||||:||||  ||:|.|..|
plant   385 QFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEDEYDEEEEQ 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	363/449 (81%)
betaTub60D	NP_523842.2	beta_tubulin	2..432	CDD:276956	351/430 (82%)
TUB1	NP_177706.1	PLN00220	1..431	CDD:215107	355/435 (82%)
TUB1	NP_177706.1	beta_tubulin	2..427	CDD:276956	351/430 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840