DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub60D and TUB8

DIOPT Version :9

Sequence 1:	NP_523842.2	Gene:	betaTub60D / 37888	FlyBaseID:	FBgn0003888	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001190373.1	Gene:	TUB8 / 832451	AraportID:	AT5G23860	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	367/450 - (81%)
Similarity:	413/450 - (91%)	Gaps:	6/450 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65
            ||||:::|.|||||||||||||::..||||||.|.|.|::|||||||:|||||||.      |::
plant     1 MREILHIQGGQCGNQIGAKFWEVVCAEHGIDSTGRYQGENDLQLERVNVYYNEASC------GRF 59

  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130
            ||||:|:|||||||:|||||||||:|||||||:||||||||||||||||||||:|:||||||||.
plant    60 VPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEA 124

  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195
            ||||||||||:.||||||||||||||||||||||||||:|.|:||.||||||||||||||||||:
plant   125 ENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSV 189

  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260
            ||||||.||...:||||||||||||||::.||:||||||:|.||||||.|||||||||:||||||
plant   190 HQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLA 254

  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325
            ||::|||||||||.|||||||||||||||||||||||||:||||||.|.|||||||||.:|:|||
plant   255 VNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRG 319

  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
            :||.|||||||:.||||||||||||||||||:.||||||.||||:||||||:|:|||:|:|:|||
plant   320 KMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSTVCDIPPTGLKMASTFIGNSTSIQEMFRRVSEQ 384

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVNQEEVE 450
            |:||||||||||||||||||||||||||||||||||||||||:||||:|...|..::|||
plant   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEEGYEYEEDEVE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	365/448 (81%)
betaTub60D	NP_523842.2	beta_tubulin	2..432	CDD:276956	355/429 (83%)
TUB8	NP_001190373.1	PLN00220	1..430	CDD:215107	359/434 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840