DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment betaTub60D and TUB9

DIOPT Version :9

Sequence 1:	NP_523842.2	Gene:	betaTub60D / 37888	FlyBaseID:	FBgn0003888	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_193821.1	Gene:	TUB9 / 827837	AraportID:	AT4G20890	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	359/449 - (79%)
Similarity:	411/449 - (91%)	Gaps:	7/449 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65
            ||||:::|.|||||||||||||:|..|||||..|...||:||||||::||:|||      |||||
plant     1 MREILHIQGGQCGNQIGAKFWEVICGEHGIDQTGQSCGDTDLQLERINVYFNEA------SGGKY 59

  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130
            ||||:|:|||||||:|:||||:||:|||||||:||||||||||||||||||||:|:||||||||.
plant    60 VPRAVLMDLEPGTMDSLRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEA 124

  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195
            ||||||||||:.||||||||||||||||||||||||||:|.|:||.||||||||||||||||||:
plant   125 ENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSV 189

  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260
            ||||||.||...:||||||||||||||::||::||||||:|.||||||.|||||||||:||||||
plant   190 HQLVENADECMVLDNEALYDICFRTLKLANPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLA 254

  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325
            ||::|||||||||.|||||||||||||.||:||||||||:||||||.|.|||||||||.:|||||
plant   255 VNLIPFPRLHFFMVGFAPLTSRGSQQYSALSVPELTQQMWDAKNMMCAADPRHGRYLTASAVFRG 319

  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
            :||.|||||||:.||||||||||||||||||::||||.|.||||:||||||:|:|||:|:|:|||
plant   320 KMSTKEVDEQMMNVQNKNSSYFVEWIPNNVKSSVCDIAPTGLKMASTFIGNSTSIQEMFRRVSEQ 384

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEAT-ADDEFDPEVNQEE 448
            |:|||||||||||||||||||||||||||||||||:||||||:|| .::|::.:..:||
plant   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVAEYQQYQDATVGEEEYEEDEEEEE 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	359/449 (80%)
betaTub60D	NP_523842.2	beta_tubulin	2..432	CDD:276956	351/429 (82%)
TUB9	NP_193821.1	PLN00220	1..431	CDD:215107	356/435 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55952
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840