Protein Alignment betaTub60D and TUBG1

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_024306672.1
• Gene: TUBG1 / 7283
• HGNCID: 12417
• Length: 538
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 157/538 - (29%)
• Similarity: 258/538 - (47%)
• Gaps: 112/538 - (20%)

  Fly     2 REIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKYV 66
            |||:.||.||||||||.:||:.:..||||...||....:....:|..|::.:|      ....|:
Human     3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQA------DDEHYI 61

  Fly    67 PRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQ--SGAGNNWAKGHYTEGAELVDNVLDVVRKE 129
            |||:||||||..:.|:.:.||.:|:.|:|....:  .|||||||.| :::|.::.:::.|::.:|
Human    62 PRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDRE 125

  Fly   130 CENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPS-PKVSDTVVEPYNATL 193
            .:..|.|:||.|.||:.||||||:|:.|:.::.:.||.:::.||||.|: .::||.||:|||:.|
Human   126 ADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLL 190

  Fly   194 SIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRK 258
            ::.:|.:|.|....:||.||..|....|.:.|||:..:|.|||..||..||.||:||.:|.||..
Human   191 TLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIG 255

  Fly   259 LAVNMVPFPRLHFFMPGFAPLTSRGS--------------------------------------- 284
            |..:::|.|||||.|.|:.|||:..|
Human   256 LIASLIPTPRLHFLMTGYTPLTTDQSVRAAFSVPGQAGPGPNRPCPSLSLFPTAPGATLCGPQGA 320

  Fly   285 -------------------------------------------------QQYRALTVPELTQQMF 300
                                                             ...|..||.::.:::.
Human   321 ALRDWHRVGDFLADLLSTLPLPLASAKEKPKGDCALSAGRVPVSLSYQVASVRKTTVLDVMRRLL 385

  Fly   301 DAKNMMAACDPRHGR-------YLTVAAVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTA 358
            ..||:|.:.    ||       |:.:..:.:|.:...:|.:.:..::.:..:.|:.|.|.:::.|
Human   386 QPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA 446

  Fly   359 V---CDIPPKGLKMSSTFIGNTTAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESN 420
            :   ....|...::|...:.|.|:|..||:|...|:..:.:|:|||..:..|.|.:..|.|.:::
Human   447 LSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEMDTS 511

  Fly   421 MNDLVSEYQQYQEATADD 438
            ...:.....:|..||..|
Human   512 REIVQQLIDEYHAATRPD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	157/538 (29%)
		beta_tubulin	2..432	CDD:276956	153/530 (29%)
TUBG1	XP_024306672.1	gamma_tubulin	3..522	CDD:276957	153/529 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810