Protein Alignment betaTub60D and TUBE1

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_057346.1
• Gene: TUBE1 / 51175
• HGNCID: 20775
• Length: 475
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 150/466 - (32%)
• Similarity: 241/466 - (51%)
• Gaps: 46/466 - (9%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEH-GIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGG- 63
            |.:.|.:|.||||||||..||::...|| .::..|||.       |.:|.::..........||
Human     1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYD-------EAISSFFRNVDTRVVGDGGS 58

  Fly    64 -------KYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDN 121
                   ....||:|:|:|.|.:..:..||...:|.....:...||:|||||.||...|:...|.
Human    59 ISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQ 123

  Fly   122 VLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVV 186
            :|:..||..|:|||||.|.:.||:|||||||:||.|:..:.:|:|:......|:.||.: .|.:.
Human   124 ILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGE-DDVIT 187

  Fly   187 EPYNATLSIHQLVENTDETYCIDNEALYDICFR------------TLK----VSNPS-------- 227
            .|||:.|::.:|.|:.|....|||::|:||..:            |:|    |::.|
Human   188 SPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHK 252

  Fly   228 --YGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRAL 290
              :..:|::|:..:..:|:..||.|.||.||.::::|:||||:||:.:....||.:.........
Human   253 KPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPR 317

  Fly   291 TVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNV 355
            .:.::....|...:.:...||:|..||..|.:.||.:.:.::...:..:  |.|..||.|.....
Human   318 RLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERL--KPSLQFVSWNQEGW 380

  Fly   356 KTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQFSAMFRRKAFLHWYTG-EGMDEMEFTEAES 419
            ||::|.:||.|...|...:.|.|.::..|..:.|:|..::::||.||.|.. |||:|..||||.|
Human   381 KTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVS 445

  Fly   420 NMNDLVSEYQQ 430
            :::.|:.||.|
Human   446 SLSALIQEYDQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	150/466 (32%)
		beta_tubulin	2..432	CDD:276956	149/465 (32%)
TUBE1	NP_057346.1	epsilon_tubulin	2..457	CDD:276959	149/465 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810