Protein Alignment betaTub60D and TUBD1

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_057345.2
• Gene: TUBD1 / 51174
• HGNCID: 16811
• Length: 453
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 117/493 - (23%)
• Similarity: 211/493 - (42%)
• Gaps: 113/493 - (22%)

  Fly     4 IVNLQAGQCGNQIGAKFWE-IISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAV-------TRS 60
            ||.:|.||||||||.:.:: ::|:.|  .|.|:           .|:..|||...       :..
Human     3 IVTVQLGQCGNQIGFEVFDALLSDSH--SSQGL-----------CSMRENEAYQASCKERFFSEE 54

  Fly    61 SGGKYVPRAILLDLEPGTMESV--RSGPYGQLFRPDNFVYGQ-------SGAGNNWAKGHYTEGA 116
            ..|..:.||:|:|:||..:..:  ::...||      :.|||       .|:|||||.|:...|.
Human    55 ENGVPIARAVLVDMEPKVINQMLSKAAQSGQ------WKYGQHACFCQKQGSGNNWAYGYSVHGP 113

  Fly   117 ELVDNVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKV 181
            ...:::::::|||.|.||...||.:..|:.||||||:|..:...:.::|.:.:.....:.|. ..
Human   114 RHEESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPY-GT 177

  Fly   182 SDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCL 246
            .:.:|:.||:.|::..|..::|.....:|:|::.||.:.:.:...|:.|:|.:::..:..|
Human   178 GEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSV---- 238

  Fly   247 RFPGQLNAD---------LRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALT----VPELTQQ 298
             |....:|:         |..|..::||.|..........|..|..|..|...|    :..|.|.
Human   239 -FQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQM 302

  Fly   299 MFDAKNMMAACDPRH----------------------GRYLTVAAVFRGRMSMKEVDEQMLAVQN 341
            :.....|....| ||                      ...:....:.||:      |.|...|:.
Human   303 LISNAKMEEGID-RHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGK------DVQSADVEG 360

  Fly   342 -KNSSYFVEWI-PNNV--------------KTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
             |:.:.:..|: |.|.              |:||       |..:|.|:     ::.|...:.:.
Human   361 FKDPALYTSWLKPVNAFNVWKTQRAFSKYEKSAV-------LVSNSQFL-----VKPLDMIVGKA 413

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEY 428
            :: ||..||::|.||..|::|.:|.::.:::..:|:.|
Human   414 WN-MFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASY 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	117/493 (24%)
		beta_tubulin	2..432	CDD:276956	117/493 (24%)
TUBD1	NP_057345.2	delta_zeta_tubulin-like	2..452	CDD:276958	117/493 (24%)
		Tubulin	2..213	CDD:278518	65/229 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900