Protein Alignment betaTub60D and TUBB8

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_817124.1
• Gene: TUBB8 / 347688
• HGNCID: 20773
• Length: 444
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 375/449 - (83%)
• Similarity: 417/449 - (92%)
• Gaps: 6/449 - (1%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65
            |||||..|.|||||||||||||:||:||.|||.|.|.|||.|||||::||||||      |||:|
Human     1 MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEA------SGGRY 59

  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130
            ||||:|:|||||||:||||||:||:||||||::||.|||||||||||||||||:::|:||||||.
Human    60 VPRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEA 124

  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195
            |:|||||||||||||||||||||||||:|||||||||||:||:|::||||||||||||||||||:
Human   125 ESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSV 189

  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260
            |||:||.|||:|||||||||||.:|||:..|:|||||||||.|||||||||||||||||||||||
Human   190 HQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254

  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325
            ||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||.||:|||
Human   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRG 319

  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
            ||.|:||||||..:|:||||||.:|:|||||||||||||:|||||:|||||.|||||||||:|||
Human   320 RMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQ 384

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVNQEEV 449
            |:||||||||||||||||||||||||||||||||||||||||:|||::|.|.|..:|||
Human   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEV 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	375/449 (84%)
		beta_tubulin	2..432	CDD:276956	363/429 (85%)
TUBB8	NP_817124.1	PTZ00010	1..427	CDD:240228	365/431 (85%)
		beta_tubulin	2..426	CDD:276956	363/429 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		13/21 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6230
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.830