Protein Alignment betaTub60D and tuba5

DIOPT Version :10

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0288686
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_997937.1
• Gene: tuba5 / 337223
• ZFINID: ZDB-GENE-030131-9167
• Length: 449
• Species: Danio rerio
• Alignment Length: 460
• Identity: 181/460 - (39%)
• Similarity: 273/460 - (59%)
• Gaps: 25/460 - (5%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIY-----VGDSDLQLERVSVYYNEASAVTRS 60
            |||.:::..||.|.|||...||:...||||..:|..     :|.||   :..:.:::|      :
Zfish     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGNMPSDKTIGKSD---DSFNTFFSE------T 56

  Fly    61 SGGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDV 125
            ..||:||||:.:||||..::.||||.|.|||.|:..:.|:..|.||:|:||||.|.|::|.||:.
Zfish    57 GSGKHVPRAVFVDLEPAVIDEVRSGTYRQLFHPEQLISGKEDAANNYARGHYTVGKEIIDMVLER 121

  Fly   126 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYN 190
            |||..:.|..||||.:.||.|||||||..:||:.::..:|..:....:::.|:|:||..||||||
Zfish   122 VRKLTDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 186

  Fly   191 ATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNAD 255
            :.|:.|..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.|
Zfish   187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVD 251

  Fly   256 LRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVA 320
            |.:...|:||:||:||.:..::|:.|.....:..|:|.|:|...|:..|.|..||||||:|:...
Zfish   252 LTEFQTNLVPYPRIHFPLVTYSPIISAEKAYHEQLSVSEITSACFEPSNQMVKCDPRHGKYMACC 316

  Fly   321 AVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPP--------KGLKMSSTFIGNT 377
            .::||.:..|:|:..:..::.|.|..||:|.|...|..:...||        ..::.:...:.||
Zfish   317 MLYRGDVVPKDVNAAIANIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNT 381

  Fly   378 TAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDP 442
            |||.|.:.|:..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|:|..||...|.
Zfish   382 TAISEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGADSTEDG 443

  Fly   443 EVNQE 447
            |..:|
Zfish   444 EEGEE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	181/460 (39%)
tuba5	NP_997937.1	PTZ00335	1..449	CDD:185562	181/460 (39%)