Protein Alignment betaTub60D and Tubb4b

DIOPT Version :10

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0288686
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_954525.2
• Gene: Tubb4b / 296554
• RGDID: 735101
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 402/449 - (89%)
• Similarity: 430/449 - (95%)
• Gaps: 8/449 - (1%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65
            |||||:||||||||||||||||:||:|||||..|.|.|||||||||::||||||      :||||
  Rat     1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEA------TGGKY 59

  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130
            ||||:|:|||||||:||||||:||:|||||||:||||||||||||||||||||||:||||||||.
  Rat    60 VPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124

  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195
            |:||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||:
  Rat   125 ESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189

  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260
            |||||||||||||||||||||||||||::.|:|||||||||.|||||||||||||||||||||||
  Rat   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254

  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 319

  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
            ||||||||||||.||||||||||||||||||||||||||:|||||:|||||:|||||||||||||
  Rat   320 RMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQ 384

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADD--EFDPEVNQE 447
            |:||||||||||||||||||||||||||||||||||||||||:|||::  ||:.|..:|
  Rat   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEE 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	402/449 (90%)
Tubb4b	NP_954525.2	PLN00220	1..427	CDD:215107	394/431 (91%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	426..445		8/18 (44%)