Protein Alignment betaTub60D and Tuba1c

DIOPT Version :10

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0288686
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_033474.1
• Gene: Tuba1c / 22146
• MGIID: 1095409
• Length: 449
• Species: Mus musculus
• Alignment Length: 465
• Identity: 181/465 - (38%)
• Similarity: 272/465 - (58%)
• Gaps: 35/465 - (7%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIY-----VGDSDLQLERVSVYYNEASAVTRS 60
            |||.:::..||.|.|||...||:...||||..:|..     :|..|   :..:.:::|..|
Mouse     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGD---DSFNTFFSETGA---- 58

  Fly    61 SGGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDV 125
              ||:||||:.:||||..::.||:|.|.|||.|:..:.|:..|.||:|:||||.|.|::|.|||.
Mouse    59 --GKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDR 121

  Fly   126 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYN 190
            :||..:.|..||||.:.||.|||||||..:||:.::..:|..:....:|:.|:|:||..||||||
Mouse   122 IRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 186

  Fly   191 ATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNAD 255
            :.|:.|..:|::|..:.:||||:||||.|.|.:..|:|.:||.|:|..:|.:|..|||.|.||.|
Mouse   187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVD 251

  Fly   256 LRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVA 320
            |.:...|:||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||||:|:...
Mouse   252 LTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACC 316

  Fly   321 AVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPP--------KGLKMSSTFIGNT 377
            .::||.:..|:|:..:..::.|.:..||:|.|...|..:...||        ..::.:...:.||
Mouse   317 LLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNT 381

  Fly   378 TAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDP 442
            |||.|.:.|:..:|..|:.::||:|||.||||:|.||:||..:|..|..:|:
Mouse   382 TAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYE------------- 433

  Fly   443 EVNQEEVEGD 452
            ||..:..|||
Mouse   434 EVGADSAEGD 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	178/461 (39%)
Tuba1c	NP_033474.1	PTZ00335	1..448	CDD:185562	181/465 (39%)
		MREC motif. /evidence=ECO:0000250|UniProtKB:P68363	1..4		2/2 (100%)