DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub60D and ben-1

DIOPT Version :9

Sequence 1:	NP_523842.2	Gene:	betaTub60D / 37888	FlyBaseID:	FBgn0003888	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_497728.2	Gene:	ben-1 / 175461	WormBaseID:	WBGene00000248	Length:	444	Species:	Caenorhabditis elegans

Alignment Length:	452	Identity:	391/452 - (86%)
Similarity:	430/452 - (95%)	Gaps:	10/452 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65
            |||||::|||||||||||||||:||:||||..:|.|.|:|||||||::||||||      :||||
Worm     1 MREIVHVQAGQCGNQIGAKFWEVISDEHGIQPDGTYKGESDLQLERINVYYNEA------NGGKY 59

  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130
            ||||:|:|||||||:||||||:||||||||||:|||||||||||||||||||||||||||||||.
Worm    60 VPRAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEA 124

  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195
            |.||||||||||||||||||||||||||||||||||||||:::|||||||||||||||||||||:
Worm   125 EGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMSSFSVVPSPKVSDTVVEPYNATLSV 189

  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260
            ||||||||||:||||||||||||||||:|||:|||||||||:|||||||||||||||||||||||
Worm   190 HQLVENTDETFCIDNEALYDICFRTLKLSNPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLA 254

  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325
            |||||||||||||||||||:::|:|.||||||.||||||||||||||||||||||||||||:|||
Worm   255 VNMVPFPRLHFFMPGFAPLSAKGAQAYRALTVAELTQQMFDAKNMMAACDPRHGRYLTVAAMFRG 319

  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390
            ||||:|||:||:.||||||||||||||||||||||||||:|||||:|||||:|||||||||||||
Worm   320 RMSMREVDDQMMNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQ 384

  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVNQEEVEGD 452
            |:||||||||||||||||||||||||||||||||||||||||||||::  |.|:  :..:||
Worm   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATAEE--DGEL--DGTDGD 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	389/448 (87%)
betaTub60D	NP_523842.2	beta_tubulin	2..432	CDD:276956	380/429 (89%)
ben-1	NP_497728.2	PLN00220	1..444	CDD:215107	391/452 (87%)
ben-1	NP_497728.2	beta_tubulin	2..426	CDD:276956	380/429 (89%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.790