Protein Alignment betaTub60D and mec-12

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_497663.1
• Gene: mec-12 / 175419
• WormBaseID: WBGene00003175
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 182/462 - (39%)
• Similarity: 274/462 - (59%)
• Gaps: 24/462 - (5%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDL--QLERVSVYYNEASAVTRSSGG 63
            |||::::..||.|.|||...||:...||||..:|....|..|  ..:..|.:::|      :..|
 Worm     1 MREVISIHIGQAGVQIGNACWELYCLEHGIQPDGQMPSDKSLGGSDDSFSTFFSE------TGSG 59

  Fly    64 KYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRK 128
            ::||||:::||||..::.:|:|.|..||.|:..:.|:..|.||:|:||||.|.|::|..||.:|:
 Worm    60 RHVPRAVMVDLEPTVIDEIRTGTYRSLFHPEQLITGKEDAANNYARGHYTIGKEIIDLTLDRIRR 124

  Fly   129 ECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATL 193
            ..:||..||||.:.||.|||||||..:||:.::..:|..:....:|:.|:|:||..||||||:.|
 Worm   125 LADNCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKAKLEFSIYPAPQVSTAVVEPYNSIL 189

  Fly   194 SIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRK 258
            :.|..:|::|.::.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:
 Worm   190 TTHTTLEHSDCSFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTE 254

  Fly   259 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVF 323
            ...|:||:||:||.:..|:|:.|.....:..|:|.|:|...|:..|.|..||||||:|:.|..:|
 Worm   255 FQTNLVPYPRIHFPLATFSPVISAEKAYHEQLSVAEITNMCFEPHNQMVKCDPRHGKYMAVCLLF 319

  Fly   324 RGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPP--------KGLKMSSTFIGNTTAI 380
            ||.:..|:|:..:..::.|.|..||:|.|...|..:...||        ..:..:...:.|||||
 Worm   320 RGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVPRAVCMLSNTTAI 384

  Fly   381 QELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVN 445
            .|.:.|:..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|:|...|...|   |
 Worm   385 AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGVDSMED---N 443

  Fly   446 QEEVEGD 452
            .|  |||
 Worm   444 GE--EGD 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	179/458 (39%)
		beta_tubulin	2..432	CDD:276956	172/439 (39%)
mec-12	NP_497663.1	PTZ00335	1..448	CDD:185562	180/460 (39%)
		alpha_tubulin	2..435	CDD:276955	173/441 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810