Protein Alignment betaTub60D and TUBA3D

DIOPT Version :9

• Sequence 1: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_525125.2
• Gene: TUBA3D / 113457
• HGNCID: 24071
• Length: 450
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 180/465 - (38%)
• Similarity: 272/465 - (58%)
• Gaps: 30/465 - (6%)

  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIY-----VGDSDLQLERVSVYYNEASAVTRS 60
            |||.:::..||.|.|||...||:...||||..:|..     :|..|   :..:.:::|..|
Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGD---DSFNTFFSETGA---- 58

  Fly    61 SGGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDV 125
              ||:||||:.:||||..::.||:|.|.|||.|:..:.|:..|.||:|:||||.|.|:||.|||.
Human    59 --GKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDR 121

  Fly   126 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYN 190
            :||..:.|..||||.:.||.|||||||..:||:.::..:|..:....:::.|:|:||..||||||
Human   122 IRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 186

  Fly   191 ATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNAD 255
            :.|:.|..:|::|..:.:||||:||||.|.|.:..|:|.:||.|:...:|.:|..|||.|.||.|
Human   187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVD 251

  Fly   256 LRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVA 320
            |.:...|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|..||||||:|:...
Human   252 LTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACC 316

  Fly   321 AVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPP--------KGLKMSSTFIGNT 377
            .::||.:..|:|:..:..::.|.:..||:|.|...|..:...||        ..::.:...:.||
Human   317 MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNT 381

  Fly   378 TAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDP 442
            |||.|.:.|:..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|:|...|
Human   382 TAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGVD----- 438

  Fly   443 EVNQEEVEGD 452
            .|..|..||:
Human   439 SVEAEAEEGE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	178/461 (39%)
		beta_tubulin	2..432	CDD:276956	172/442 (39%)
TUBA3D	NP_525125.2	PTZ00335	1..440	CDD:185562	176/455 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810