DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp3 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	XP_030100613.1	Gene:	Acsbg1 / 94180	MGIID:	2385656	Length:	754	Species:	Mus musculus

Alignment Length:	809	Identity:	168/809 - (20%)
Similarity:	270/809 - (33%)	Gaps:	262/809 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSENEKRPDLEDQ---------DQDQNQEQ------AGGRKMEILLELNLKQKLATRLGTILLAT 50
            :|.:...||..|.         .||.:|.:      .||......|.||||.:...| .::..::
Mouse    12 LSRDSNMPDSRDDQQQGASLGTSQDNSQTRFVSRLLPGGPGCVRKLSLNLKYQQGIR-PSVRSSS 75

  Fly    51 VIFG---------------------AFCWDNALASL-TLGAVVALLLRNPTFVFALVMTASRDLK 93
            :|.|                     |...|.|..:| |..|...:.||...|      ...|...
Mouse    76 LIDGQTLSKESPSHGLELSAPEKARAASLDGAEEALWTTRADGRVRLRLEPF------CTQRPYT 134

  Fly    94 AFQRFV-ALNIY-------LLRKDRGGFTVARCFQDQARRRPKKTCFVMDDRHLSFAEALEFSQK 150
            ..|.|. ||:.|       ..|||:.                         ..:|:.:....::|
Mouse   135 VHQMFYEALDKYGNLSALGFKRKDKW-------------------------ERISYYQYYLIARK 174

  Fly   151 IAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIKVANAKALI 215
            :|..|...||||...||:|.....|:....:|....|.|...|.:....|:..:......|..::
Mouse   175 VAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYISHDCRANVIV 239

  Fly   216 VGS--ELLDVLVSLREKEQLDEVPIYQ----------YTDDEVRGVAGHDLLPGAVDLVTALKTQ 268
            |.:  :|..:|...::...|..|.|||          ||.:|:..: |.::...|:|.:  :.||
Mouse   240 VDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIEL-GQEVPEEALDAI--IDTQ 301

  Fly   269 KKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMS-----AGSYYMLKMSSDDVVY 328
            :    |:..|        :.||||||||.||..:::.....:.:     ||.....:: ..:||.
Mouse   302 Q----PNQCC--------VLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEV-QQEVVV 353

  Fly   329 DPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSP 393
            ..|||.|.|..|.                     :.|        |..|:..::|      ...|
Mouse   354 SYLPLSHIAAQIY---------------------DLW--------TGIQWGAQVC------FADP 383

  Fly   394 DQQKHNLRLMYGNGLR----------PQIWSQFVRRFGIPHIGEIYGATEG-------------- 434
            |..|..|    .|.||          |::|.:.:.|     |.|: .|..|
Mouse   384 DALKGTL----VNTLREVEPTSHMGVPRVWEKIMER-----IQEV-AAQSGFIRRKMLLWAMSVT 438

  Fly   435 --------NSNLINITNRVG----------AIGFVP----VYGSSLYPVQV------LRCDEYTG 471
                    :::|...|:|:.          |:||..    .||::....:.      |....|.|
Mouse   439 LEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFFLGLNIRLYAG 503

  Fly   472 ELLKDSKG-HCI------------RCQPGQAGLLVGKVDA---------RRAVSAFHGYADKGAS 514
            ..|.:|.| |.:            |..||....||.: ||         .|.:  |.||.:   .
Mouse   504 YGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQ-DADGIGEICLWGRTI--FMGYLN---M 562

  Fly   515 EQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGD-TFRWRGENVATQEVEAIITNCVGLED 578
            |.|....:.:.|  :.::|||...|..|:.|...|..: .....||||....:|..:.
Mouse   563 EDKTCEAIDSEG--WLHTGDMGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVK------- 618

  Fly   579 CVVYGVQIPHVEGKAGMAAIVDPERKVDMDYLSVV--LRGSLPPYARPLFIRLLDEIPRTATFKL 641
                 :::|.:..    |.::..:||    :||::  |:.:|.|........|.::.........
Mouse   619 -----MELPIISS----AMLIGDQRK----FLSMLLTLKCTLDPETSEPTDSLTEQAVEFCQRVG 670

  Fly   642 KKRELAKEAYDIGQLSDPIYYLNRDGIYR 670
            .|.....|.  :||..:.:|....:||.|
Mouse   671 SKASTVSEI--VGQRDEAVYQAIHEGIQR 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	142/683 (21%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	127/610 (21%)
Acsbg1	XP_030100613.1	ACSBG_like	155..749	CDD:341256	136/659 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839052
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930