DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fatp3 and Slc27a1

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	XP_006253015.1	Gene:	Slc27a1 / 94172	RGDID:	620927	Length:	649	Species:	Rattus norvegicus

Alignment Length:	615	Identity:	262/615 - (42%)
Similarity:	380/615 - (61%)	Gaps:	18/615 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 FVFALVMTASRDLKAFQRFVALNIYLLRKDRGGFTVARCFQDQARRRPKKTCFVMDDRHL--SFA 142
            |:..:..||.|||......:.:.:.|.|..|.|.|:.|.||..|:|:|::...|.....:  :||
  Rat    46 FLRIVCKTARRDLFGLSVLIRVRLELRRHRRAGDTIPRIFQAVAQRQPERLALVDASSGICWTFA 110

  Fly   143 EALEFSQKIAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIK 207
            :...:|..:|..|...|...||.||:.:|.|.|:..:||||::.||:.||:|.|||.|.|...:.
  Rat   111 QLDTYSNAVANLFLQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLG 175

  Fly   208 VANAKALIVGSELLDVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALKTQKKLE 272
            .:.|||||.|.|:...:..:  .|||.:         .:......||.|.:|...|.|......|
  Rat   176 TSAAKALIYGGEMAAAVAEV--SEQLGK---------SLLKFCSGDLGPESVLPDTQLLDPMLAE 229

  Fly   273 LPS---AVCPGEAR-SKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSDDVVYDPLPL 333
            .|:   |..||:.. .:|.|:||||||||||||::.:.|:..::|..::...|.::||:||.|||
  Rat   230 APTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRANDVLYDCLPL 294

  Fly   334 YHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKH 398
            ||:||.|:|||..|:.|.||||||||||..||.||.::||||.|||||:|||||.......:::|
  Rat   295 YHSAGNIMGVGQCIIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVERRH 359

  Fly   399 NLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQV 463
            ::||..||||||.||.:|.:|||:..|||.|||||.|.::.|:..:||:.||.....:.:||:::
  Rat   360 HVRLAVGNGLRPAIWEEFTQRFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILTHVYPIRL 424

  Fly   464 LRCDEYTGELLKDSKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDV 528
            ::.:|.|.|.|:||:|.||.||||:.|||||:::.:..:..|.||....|:.:|:..:||..||.
  Rat   425 VKVNEDTMEPLRDSQGLCIPCQPGEPGLLVGQINQQDPLRRFDGYVSDSATNKKIAHSVFRKGDS 489

  Fly   529 FFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKA 593
            .:.|||::|.|.|||.||:||:|||||||||||:|.||||:::..:|..|..||||.:|.|||||
  Rat   490 AYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKA 554

  Fly   594 GMAAIVDPERKVDMDYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKLKKRELAKEAYDIGQLSD 658
            |||||.||..::|.:.:...|:..|..||:|:|:|||.::..|.|||::|..|.:|.:|..|.||
  Rat   555 GMAAIADPHNQLDPNSMYQELQKVLASYAQPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSD 619

  Fly   659 PIYYLN-RDGIYRPLSQEQHELLRSGKAGL 687
            .:::|: :.|.|.||.:..|..:.:|...|
  Rat   620 RLFFLDLKQGRYLPLDERVHARICAGDFSL 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	257/600 (43%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	232/522 (44%)
Slc27a1	XP_006253015.1	PRK08279	45..649	CDD:236217	261/613 (43%)
Slc27a1	XP_006253015.1	AFD_class_I	107..614	CDD:302604	232/517 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342873
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1179
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63225
OrthoDB	1	1.010	-	-		D312083at2759
OrthoFinder	1	1.000	-	-		FOG0000388
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100576
Panther	1	1.100	-	-	O	PTHR43107
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X222
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.720