Protein Alignment Fatp3 and FAT1

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_009597.2
• Gene: FAT1 / 852329
• SGDID: S000000245
• Length: 669
• Species: Saccharomyces cerevisiae
• Alignment Length: 684
• Identity: 192/684 - (28%)
• Similarity: 312/684 - (45%)
• Gaps: 113/684 - (16%)

  Fly    81 VFALVMTASRDLKAFQRFVALNIYLLRKDRGGFTVARCFQDQARRRPKKT-------------CF 132
            ||||    ||......|.:.|.|..::|.. |:.....|.:..|:...|.             |:
Yeast     8 VFAL----SRIFLLLFRLIKLIITPIQKSL-GYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCY 67

  Fly   133 VMDDR-------------------HLS------FAEALEFSQKIAGYFS--------------DR 158
            ::|.|                   ||:      .||..||..:...|..              |.
Yeast    68 IIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDY 132

  Fly   159 GLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIKVANAKALIVGSELLDV 223
            .::.||.||:....:..:..:||.|..:|.|.|.:|.|.:|..|:||:|::|...:.:..   |.
Yeast   133 NVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDP---DA 194

  Fly   224 LVSLREKEQ-----LDEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALKTQKKLELPSAVCPGEAR 283
            ...:||.|:     |.:|.:....:.::.    |:||              ..:.|..:.....|
Yeast   195 SNPIRESEEEIKNALPDVKLNYLEEQDLM----HELL--------------NSQSPEFLQQDNVR 241

  Fly   284 SKL--------LYVYTSGTTGLPKAAVITNLRFLFMSAGSY---YMLKMSSDDVVYDPLPLYHTA 337
            :.|        :.:||||||||||:|:::   :...|.|..   ::|.|:::..|:..:||:|:.
Yeast   242 TPLGLTDFKPSMLIYTSGTTGLPKSAIMS---WRKSSVGCQVFGHVLHMTNESTVFTAMPLFHST 303

  Fly   338 GGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKHNLRL 402
            ..::|....:.:|..:.|..||||..||........|..||:||:|||||.|..|..::.|.:::
Yeast   304 AALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKV 368

  Fly   403 MYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSL-----YPVQ 462
            .|||||||.||..|.:||.|..|||.|.|||..............||....||:.:     :...
Yeast   369 AYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQT 433

  Fly   463 VLRCDEYTGELL-KDSKGHCIRCQPGQAGLLVGKV-DARRAVSAFHGY-ADKGASEQKLLRNVFT 524
            ::|.|.....:: ::|||.|.....|:.|.::.:: ..::..::|.|| .:...::.|::|:||.
Yeast   434 LVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFR 498

  Fly   525 SGDVFFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIIT--NCVGLEDCVVYGVQIP 587
            .||.::..||::..|..|.:||.||.||||||:.|||:|.|||..:|  |.......:|.|:::|
Yeast   499 RGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVP 563

  Fly   588 HVEGKAGMAAIVDPERKVDMDYLSVVLRGS-----LPPYARPLFIRLLDEIPRTATFKLKKRELA 647
            ..||:||.|.|...:..:|:...:.:|..|     ||.||.|||::.:|||..|...|:.|:...
Yeast   564 KYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYR 628

  Fly   648 KEAYDIG-QLSDPIYYLNRDGIYRPLSQEQHELL 680
            ::....| ..:|.|::|.....|..|:....|.:
Yeast   629 EQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAI 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	169/586 (29%)
FAT1	NP_009597.2	FATP_chFAT1_like	107..634	CDD:341260	163/550 (30%)