DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp3 and AAE12

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_176764.1	Gene:	AAE12 / 842901	AraportID:	AT1G65890	Length:	578	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	129/567 - (22%)
Similarity:	226/567 - (39%)	Gaps:	86/567 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 PKKTCFVMDDRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMETRLEYPCIW---LGLSQLGV 188
            |.:|..:......::.:..:...::|.......:.:.|.|:::....   |.::   ..:...|.
plant    28 PNRTSIIYGKTRFTWPQTYDRCCRLAASLISLNIGKNDVVSVVAPNT---PAMYEMHFAVPMAGA 89

  Fly   189 ITALINSNLRGESLLHSIKVANAKALIV-------GSELLDVLVSLREKEQLDEVPIYQYTDDEV 246
            :...||:.|...|:...::.|..|.|.:       ..|:|.:|.|  |...|:...|:.:..|..
plant    90 VLNPINTRLDATSIAAILRHAKPKILFIYRSFEPLAREILQLLSS--EDSNLNLPVIFIHEIDFP 152

  Fly   247 RGVAGHDLLPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFM 311
            :.|:..:   ...:.:........|.|....|..:....:...||||||..||..||::......
plant   153 KRVSSEE---SDYECLIQRGEPTPLLLARMFCIQDEHDPISLNYTSGTTADPKGVVISHRGAYLS 214

  Fly   312 SAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVA 376
            :..:....:|.:..|....||::|..|.....|.|...|::|.:| ..:|...:.:.:.||.|
plant   215 TLSAIIGWEMGTCPVYLWTLPMFHCNGWTFTWGTAARGGTSVCMR-HVTAPEIYKNIEMHNVT-- 276

  Fly   377 QYIGELCRYLLATSYSPDQQKHNLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINI 441
                .:|  .:.|.:       |: |:.||.|      ....|.|..|:     .|.|:.....:
plant   277 ----HMC--CVPTVF-------NI-LLKGNSL------DLSHRSGPVHV-----LTGGSPPPAAL 316

  Fly   442 TNRVGAIGF--VPVYGSSLYPVQVLRC---DEYTGELLKDSKGHCIRCQPGQAGLLVGKVDAR-- 499
            ..:|..:||  :..||.:.....||.|   ||:  ..|.:::...::.:.|.:.|.:.:||.|
plant   317 VKKVQRLGFQVMHAYGLTEATGPVLFCEWQDEW--NRLPENQQMELKARQGLSILGLTEVDVRNK 379

  Fly   500 -------RAVSAFHGYADKGASEQK-LLRNVFTSGDVF----FNSGDMVVRDILGYFYFKDRTGD 552
                   |..........||:|..| .|:|...:.:.|    .||||:.|....|:...|||:.|
plant   380 ETQESVPRDGKTMGEIVMKGSSIMKGYLKNPKATYEAFKHGWLNSGDVGVIHPDGHVEIKDRSKD 444

  Fly   553 TFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPH-VEGKAGMAAIV---------DPERKV-- 605
            .....|||:::.|||.||.....:.:..|  |.:|| ..|:...|.:|         |.|.|:
plant   445 IIISGGENISSVEVENIIYKYPKVLETAV--VAMPHPTWGETPCAFVVLEKGETNNEDREDKLVT 507

  Fly   606 -DMDYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKL---KKRELAK 648
             :.|.:. ..|.:||.:..|..:..|||:|:....|:   |.|::||
plant   508 KERDLIE-YCRENLPHFMCPRKVVFLDELPKNGNGKILKPKLRDIAK 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	129/567 (23%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	127/558 (23%)
AAE12	NP_176764.1	PLN03102	1..578	CDD:215576	129/567 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312083at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920