DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp3 and AAE1

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_564116.1	Gene:	AAE1 / 838644	AraportID:	AT1G20560	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	573	Identity:	121/573 - (21%)
Similarity:	211/573 - (36%)	Gaps:	141/573 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 KIAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSI--KVANAK 212
            :||...|..|:..||.|::|.........:..|:...|.:  |...|:|.:|.|.::  :.:..|
plant    53 RIASALSQLGISTGDVVSVLAPNVPAMVELHFGVPMAGAL--LCTLNIRHDSSLVAVLLRHSGTK 115

  Fly   213 ALIVGSELLDVLVSLRE--KEQLDEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALK--TQKKLEL 273
            .:....:.|.:.....|  ..:.|:|||..             |:|..:....:.|  :::.:|.
plant   116 VIFADHQFLQIAEGACEILSNKGDKVPILV-------------LIPEPLTQSVSRKKRSEEMMEY 167

  Fly   274 PSAVCPGEARSKLL----------YVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSDDVVY 328
            ...|..|::..:::          ..||||||..||..|.::......|..:..:.:|.|.....
plant   168 EDVVAMGKSDFEVIRPTDECDAISVNYTSGTTSSPKGVVYSHRGAYLNSLAAVLLNEMHSSPTYL 232

  Fly   329 DPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSP 393
            ...|::|..|..:..|...:.|:.:.|| ..:|:..:.:..:|..|   ::|.....|.....:|
plant   233 WTNPMFHCNGWCLLWGVTAIGGTNICLR-NVTAKAIFDNISQHKVT---HMGGAPTILNMIINAP 293

  Fly   394 DQQK----------------------------------HNLRLMYGNGL----RPQIWSQFVR-- 418
            :.::                                  :.|...||.|.    :|: |....|
plant   294 ESEQKPLPGKVSFITGAAPPPAHVIFKMEELGFSMFHSYGLTETYGPGTICTWKPE-WDSLPREE 357

  Fly   419 ------RFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLKDS 477
                  |.|:.|:|                               |..:||           ||.
plant   358 QAKMKARQGVNHLG-------------------------------LEEIQV-----------KDP 380

  Fly   478 KGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILG 542
            .  .:|..|.. |:.:|:| ..|..:..:||    ....:..:..|..|  :|.|||:.|:...|
plant   381 V--TMRTLPAD-GVTMGEV-VFRGNTVMNGY----LKNPEATKEAFKGG--WFWSGDLGVKHPDG 435

  Fly   543 YFYFKDRTGDTFRWRGENVATQEVEAIITN--CVGLEDCVVYGVQIPHVEGKAGMAAI-VDPERK 604
            |...|||:.|.....|||:::.|||:.:..  || ||..||  .:.....|:...|.: :....|
plant   436 YIELKDRSKDIIISGGENISSIEVESTLFTHPCV-LEAAVV--ARPDEYWGETACAFVKLKDGSK 497

  Fly   605 VDMDYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKLKKRELAKEAYDIGQLS 657
            ...:.|....|..||.|..|..| :.:::|:|:|.|::|..|..:|..:..||
plant   498 ASAEELISYCRDRLPHYMAPRSI-VFEDLPKTSTGKVQKFVLRTKAKALVSLS 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	121/573 (21%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	119/567 (21%)
AAE1	NP_564116.1	PRK08162	4..545	CDD:236169	119/567 (21%)
AAE1	NP_564116.1	ttLC_FACS_AEE21_like	13..540	CDD:213326	118/562 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312083at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920