Protein Alignment Fatp3 and ACSBG2

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 698
• Identity: 137/698 - (19%)
• Similarity: 233/698 - (33%)
• Gaps: 224/698 - (32%)

  Fly    77 NPTFVFALVMTASRDLKAFQRFVALNIYLLRKDRGG------FTVARCFQDQ----------ARR 125
            |.|.|...:.|..||.:.          |||..:.|      .|:...|::.          |.:
Human    19 NKTEVTPRLWTTCRDGEV----------LLRLSKHGPGHETPMTIPEFFRESVNRFGTYPALASK 73

  Fly   126 RPKKTCFVMDDRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVIT 190
            ..||.      ..|:|.:..|..:|.|......||||...|.:|.....|:....:|....|.:.
Human    74 NGKKW------EILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLC 132

  Fly   191 ALINSNLRGESLLHSIKVANAKALIV-GSELLDVLVSLREK--EQLDEVPIYQYTDDEVRGVAGH 252
            ..|.:....|...:.|..|....|:| ..:.|..::|:.:.  |.|..:..|:....:...:...
Human   133 VGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLYSW 197

  Fly   253 DLLPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYY 317
            |      |.:...::....:|...:...:|....:.:|||||||:||..::::....:::.....
Human   198 D------DFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTK 256

  Fly   318 MLKMS-SDDVVYDPLPLYHTAGGIVGVGNAI-------------LNGSTV--------------- 353
            ..|:: ..:.|...|||.|.|..::.:...|             |.|:.|
Human   257 DFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVP 321

  Fly   354 -------VLRKKFSARNFWLD-------------------CDRHNCTVAQYIGELCRYLLATSYS 392
                   .:.||.||::..|.                   ..::|..|:        |.:|.:..
Human   322 QIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVS--------YRMAKTLV 378

  Fly   393 PDQQKHNLRL----MYGNGLRP--QIWSQFVRRFGIPHIGEIYGATE--GNSNLINITNRVGAIG 449
            ..:.|.:|.|    .:.:|..|  |..::|.....|| |||:||.:|  |...:.|..|
Human   379 FSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSLDIP-IGELYGLSESSGPHTISNQNN------ 436

  Fly   450 FVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQAGL----LVGKVDARRAVSAFHGYAD 510
                       .::|.|    |::|...|.  :..|..:.|:    |.|:       ..|.||.:
Human   437 -----------YRLLSC----GKILTGCKN--MLFQQNKDGIGEICLWGR-------HIFMGYLE 477

  Fly   511 KGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGD----TFRWRGENVATQEVEAIIT 571
               ||.:....:...|  :.:|||:...|.||:.|.   ||.    .....||||....||.::.
Human   478 ---SETETTEAIDDEG--WLHSGDLGQLDGLGFLYV---TGHIKEILITAGGENVPPIPVETLVK 534

  Fly   572 NCVGLEDCVVYGVQIPHVEGKAGMAAIVDPERKVDMDYLSVVLRGSLPPYARPLFIRLLDEIPRT 636
            .            :||.:..    |.:|..:.|    :||::|
Human   535 K------------KIPIISN----AMLVGDKLK----FLSMLL---------------------- 557

  Fly   637 ATFKLKKRELAKEAYD----------------------IGQLSDPIYY 662
             |.|.:..:::.|..|                      |.:..||:.|
Human   558 -TLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVY 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	118/612 (19%)
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	124/634 (20%)