Protein Alignment Fatp3 and Acsl4

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_997508.1
• Gene: Acsl4 / 50790
• MGIID: 1354713
• Length: 711
• Species: Mus musculus
• Alignment Length: 616
• Identity: 133/616 - (21%)
• Similarity: 228/616 - (37%)
• Gaps: 172/616 - (27%)

  Fly   159 GLERGDCVALLMETRLEYPCIWLGLSQ------LGVITALINSNLRGESLLHSIKVANAKALIVG 217
            ||:..:.:|:..|||.|    |:..:|      ..::|  :.:.|..|:::|.:..:.|..||..
Mouse   146 GLKPKNTIAIFCETRAE----WMIAAQTCFKYNFPLVT--LYATLGREAVVHGLNESEASYLITS 204

  Fly   218 SELLDVLVSLREKEQLDEVPIYQ---YTDDEV-------RGVAGHDLLPGAVDLVTALKTQKKLE 272
            .|||:    .:.|..|.::...:   |.|::.       .|:..|.:  .:|:.:.| |.:....
Mouse   205 VELLE----SKLKAALVDINCVKHIIYVDNKTINRAEYPEGLEIHSM--QSVEELGA-KPENLSV 262

  Fly   273 LPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLK-MSSDDVVYDPLPLYH- 335
            .||...|.:   ..:.:||||:||.||..::.:...:....|....:. :...|.....|||.|
Mouse   263 PPSRPTPSD---MAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHV 324

  Fly   336 ----------TAGGIVGVGNAI-LNGSTVVLRKKFSARNFWLDC---------------DRHNCT 374
                      |.|..:|..:.: |:..:..::|....     ||               ||....
Mouse   325 LELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKG-----DCTVLKPTLMAAVPEIMDRIYKN 384

  Fly   375 VAQYIGELCRYLLAT------SYSPDQQKH---------------------NLRLMYGNG--LRP 410
            |...:.|: .|:..|      .|..:|.|.                     |:|:|...|  |.|
Mouse   385 VMSKVQEM-NYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSP 448

  Fly   411 QIWSQFVRRFGIPHIGEIYGATE--GNSNLINITN----RVGAIGFVPVYGSSLYPVQVLRCDEY 469
            |........|..| ||:.||.||  |...:..:|:    ||||               .|.|.|.
Mouse   449 QTHRFMNVCFCCP-IGQGYGLTESCGAGTVTEVTDYTTGRVGA---------------PLICCEI 497

  Fly   470 TGELLKD--SKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNS 532
            .   |||  ..|:.:..:|...|.:|  :..:.....:....:|.|.:..:..|    |..:|.:
Mouse   498 K---LKDWQEGGYTVHDKPNPRGEIV--IGGQNISMGYFKNEEKTAEDYCVDEN----GQRWFCT 553

  Fly   533 GDMVVRDILGYFY------FKDRTGDTFRWR-GENVATQEVEAIITNCVGLEDCVVYGVQ----- 585
            ||      :|.|:      ..||..|..:.: ||.|:..:|||.:.||..:::...:...
Mouse   554 GD------IGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYV 612

  Fly   586 IPHVEGKAGMAAIVDPERKVDMDYLSV---------VLRG--------SLPPYARPLFIRLLDE- 632
            |..|........::..::.|:..::.:         :|:.        .|..:..|:.:||..|
Mouse   613 ISFVVPNQKKLTLLAQQKGVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEP 677

  Fly   633 -IPRTA----TFKLKKRELAKEAY--DIGQL 656
             .|.|.    .||||::|| |..|  ||.::
Mouse   678 WTPETGLVTDAFKLKRKEL-KNHYLKDIERM 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	131/611 (21%)
Acsl4	NP_997508.1	LC_FACS_euk1	121..696	CDD:341294	127/602 (21%)