DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp3 and CG9993

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	126/578 - (21%)
Similarity:	229/578 - (39%)	Gaps:	98/578 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 VARCFQDQARRRPKKTCFVMD--DRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMETRLEYP 177
            :.|.:.|       |...|.|  ...|:.::.||.|:::|..|....|:|||.|.:..:....
  Fly    35 ILRLYSD-------KVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTY-- 90

  Fly   178 CIWLGLSQLGVITALINS--------NLRGESLLHSIKVANAKALIVGSELLDVLVSLREKEQL- 233
                 |::: ||.||:|.        :...|:..:..::...|.:....:....|.:::...:.
  Fly    91 -----LTEV-VIAALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSLKFK 149

  Fly   234 DEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYT-SGTTGL 297
            .|:.:...|...||.:  .|||   .|..|.. .:|.|    ..||........::.| ||.|||
  Fly   150 TEIILLTGTLPGVRNI--QDLL---ADGCTGY-DEKTL----FACPHLCGDDTAFIITSSGVTGL 204

  Fly   298 PKAAVITNLRFLFMSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNG-STVVLRKKFSA 361
            || .|..:.|.|..||....:  .:||.|::...|||..: .|..:..:::|| ..::..:.||.
  Fly   205 PK-GVTRSHRSLLNSAKIPQL--FTSDTVLFCFSPLYWIS-CIFTLLASLVNGCRRIITNRPFSV 265

  Fly   362 RNFWLDCDRHN----CTVAQYIGELCRYLLATSYSPDQQKHNLRLM-------YGNGLRPQIWSQ 415
            ..|....:||.    .||..::..|.:       ||::|:...::.       .|:.:...||.|
  Fly   266 AYFADLVERHQVSFVLTVPHHMALLAK-------SPERQELAAKMQCVQSFVCSGSKVPMGIWRQ 323

  Fly   416 FVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGH 480
            .....|......:||.||......|:...:|:      .|..|..|||...|.: |:.|
  Fly   324 LYELLGANRFAVLYGLTETGGISKNVGGPLGS------EGRLLRNVQVRVVDPH-GQSL------ 375

  Fly   481 CIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFY 545
                .|.|.|.::.:::.|     :.||.......|..:    |....:..:||....|..|..:
  Fly   376 ----GPNQTGQILVRLNLR-----WGGYYHNPQETQVTV----TPDGKWLLTGDHGYFDDEGCLH 427

  Fly   546 FKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKAGMAAIVDPERKVDMDYL 610
            |:.|..|.|::....:..:::|.:|.:..|:.:..|:|:. ..|.......|:|..|.::.....
  Fly   428 FQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIP-DEVSTNLTACAVVRNEDELGAQLT 491

  Fly   611 SVVLRGSLPPYARPLF-----IRLLDEIPRTATFKLKKRELAKEAYDIGQLSDPIYYL 663
            ...::|.:..:....|     :..:|.:|:|...|:::|::      ..|||:...:|
  Fly   492 EADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRRKI------WSQLSEATTHL 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	126/578 (22%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	117/543 (22%)
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	122/559 (22%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	118/538 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840