DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp3 and pdgy

DIOPT Version :9

Sequence 1:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	129/560 - (23%)
Similarity:	226/560 - (40%)	Gaps:	84/560 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 RRPKKTCFVMDDRHLSFAEALEFSQKIAGYFSDR-GLERGDCVALLMETRLEYPCIWLGLSQLGV 188
            ||....| |:.||..:||:..:.|...|.....: .|::.|.:|:.:....|||...||..:.|:
  Fly    90 RRTAAVC-VITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGL 153

  Fly   189 ITALINSNLRGESLLHSIKVANAKALIVGSELLDVLVSLREKEQL--DEVPIYQYTDDEVRGVAG 251
            ....:|.....:.:...:..:.|| .:||:  :....:|.:..:|  .::||     ..||..|.
  Fly   154 TVTTVNPVYTPDEIARQLTFSGAK-FLVGT--VSGFATLSQASKLVGRQIPI-----AVVRTSAE 210

  Fly   252 HDLLPGAVDLVTALKTQ----KKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLF-- 310
            ..|..||:|......||    :.|:.|.   ...|...:...::||||||||..::::.....
  Fly   211 EALPEGAIDFSELTSTQNVRYEDLKAPK---EASADDMVFLPFSSGTTGLPKGVMLSHNNITSNC 272

  Fly   311 -MSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCT 374
             ....|..:..|...:.:...||.:|..|..|.:.:.:..|..:.....|...:|....|::..:
  Fly   273 EQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGS 337

  Fly   375 VAQYIGELCRYLLATSYSPDQQKHNLRLMYGNGLRP---QIWSQFVRRFGIPHIGEIYGATEGNS 436
            :...:..:..:::.......:...:|:::. :|..|   ....:|:.:|......:.||.||. |
  Fly   338 ILNLVPPIALFMINHPKLTQETAPHLKVVM-SGAAPIGQHDVERFLNKFPNTVFKQGYGMTEA-S 400

  Fly   437 NLINIT---NRVGA----------IGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQ 488
            .::.:|   |:|.|          ...||:.||....|.    ...||||       |:|.....
  Fly   401 PVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAKGVG----PRTTGEL-------CVRGPQVM 454

  Fly   489 AGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGDT 553
            ||.|  ..|....|:.:.|             |...||||.|...|       |.||..||..:.
  Fly   455 AGYL--NNDEANQVTFYPG-------------NWLRSGDVAFYDED-------GLFYITDRMKEL 497

  Fly   554 FRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPH-VEGKAGMAAIVDPE-RKVDMDYLSVVLRG 616
            .:.:|..|...|:||::.:...:.:..|:|  ||| ..|:|..|.:|..: .|...:.:|..:..
  Fly   498 IKVKGFQVPPAELEAVLRDHPKILEAAVFG--IPHEFNGEAPRAIVVLRQGEKASAEEISAYVAE 560

  Fly   617 SLPPYAR----PLFIRLLDEIPRTATFKLKKRELAKEAYD 652
            .:..|.:    .:|:   ||:|:..|.|:.:|||.::..|
  Fly   561 RVAHYKKLEGGVIFV---DEVPKNPTGKILRRELKEKFSD 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	129/560 (23%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	125/549 (23%)
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	128/556 (23%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	121/538 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840