Protein Alignment Fatp3 and ACSL4

DIOPT Version :9

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 131/627 - (20%)
• Similarity: 231/627 - (36%)
• Gaps: 184/627 - (29%)

  Fly   145 LEFSQKIAGYFSD---RGLERGDCVALLMETRLEYPCIWLGLSQ------LGVITALINSNLRGE 200
            ||.::::..:.|.   .||:..:.:|:..|||.|    |:..:|      ..::|  :.:.|..|
Human   135 LEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAE----WMIAAQTCFKYNFPLVT--LYATLGKE 193

  Fly   201 SLLHSIKVANAKALIVGSELLDVLVSLREKEQLDEVPIYQ---YTDDEVRGVAGHDLLPGAVDLV 262
            :::|.:..:.|..||...|||:    .:.|..|.::...:   |.|::....|.:   |...: :
Human   194 AVVHGLNESEASYLITSVELLE----SKLKTALLDISCVKHIIYVDNKAINKAEY---PEGFE-I 250

  Fly   263 TALKTQKKLEL--------PSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYML 319
            .::::.::|..        ||...|.:   ..:.:||||:||.||..::.:...:....|....:
Human   251 HSMQSVEELGSNPENLGIPPSRPTPSD---MAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERI 312

  Fly   320 K-MSSDDVVYDPLPLYH-----------TAGGIVGVGNAI-LNGSTVVLRKKFSARNFWLDC--- 368
            . :...|.....|||.|           |.|..:|..:.: |:..:..::|....     ||
Human   313 PGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKG-----DCTVL 372

  Fly   369 ------------DRHNCTVAQYIGELCRYLLAT------SYSPDQQKH----------------- 398
                        ||....|...:.|: .|:..|      .|..:|.|.
Human   373 KPTLMAAVPEIMDRIYKNVMSKVQEM-NYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKA 436

  Fly   399 ----NLRLMYGNG--LRPQIWSQFVRRFGIPHIGEIYGATE--GNSNLINITN----RVGAIGFV 451
                |:|:|...|  |.||........|..| ||:.||.||  |...:..:|:    ||||
Human   437 LLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP-IGQGYGLTESCGAGTVTEVTDYTTGRVGA---- 496

  Fly   452 PVYGSSLYPVQVLRCDEYTGELLKD--SKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGAS 514
                       .|.|.|..   |||  ..|:.|..:|...|.:|  :..:.....:....:|.|.
Human   497 -----------PLICCEIK---LKDWQEGGYTINDKPNPRGEIV--IGGQNISMGYFKNEEKTAE 545

  Fly   515 EQKLLRNVFTSGDVFFNSGDMVVRDILGYFY------FKDRTGDTFRWR-GENVATQEVEAIITN 572
            :..:..|    |..:|.:||      :|.|:      ..||..|..:.: ||.|:..:|||.:.|
Human   546 DYSVDEN----GQRWFCTGD------IGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKN 600

  Fly   573 CVGLEDCVVYGVQIPHVEGKAGMAAIVDPERK-----------------------VDMDYLSVVL 614
            |..:::...:.     ...::.:.:.|.|.:|                       ::.:.|..:.
Human   601 CPLIDNICAFA-----KSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIR 660

  Fly   615 RGS----LPPYARPLFIRLLDE--IPRTA----TFKLKKREL 646
            ..:    |..:..|:.:||..|  .|.|.    .||||::||
Human   661 EAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKEL 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	131/627 (21%)
		hsFATP4_like	136..653	CDD:213305	131/627 (21%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	131/627 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930