Protein Alignment Fatp3 and SLC27A2

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_003636.2
• Gene: SLC27A2 / 11001
• HGNCID: 10996
• Length: 620
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 242/626 - (38%)
• Similarity: 351/626 - (56%)
• Gaps: 45/626 - (7%)

  Fly    70 VVALLLRNPTFVFALVMTASRDLKAFQRFVAL--NIYLLRKDRGGFTVARCFQDQARRRPKKTCF 132
            |:|.||..|..|........:|:..|.:..|:  .:....|.|...|:.|.|.::||:.|.|...
Human     8 VLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFL 72

  Fly   133 VMDDRHLSFAEALEFSQKIAGYFSDR-GLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSN 196
            :..|..|::|:....|.::|....|. ||.:||||||||.....|..:||||.:||...|.:|.|
Human    73 LFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYN 137

  Fly   197 LRGESLLHSIKVANAKALIVGSELL----DVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPG 257
            :|.:||||..:...||.|:|..||.    ::|.||::    |:|.||.     |...:..|.:..
Human   138 IRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKK----DDVSIYY-----VSRTSNTDGIDS 193

  Fly   258 AVDLVTALKTQKKLELPSAVCPGEARSKL------LYVYTSGTTGLPKAAVITNLRFLFMSAGSY 316
            .:|.|..:.|:.        .|...||::      ||:||||||||||||:||:.| ::...|..
Human   194 FLDKVDEVSTEP--------IPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQR-IWYGTGLT 249

  Fly   317 YMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGE 381
            ::..:.:|||:|..||.||:|..::|:...|:.|:|:.||.||||..||.||.::|.||.|||||
Human   250 FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGE 314

  Fly   382 LCRYLLATSYSPDQQKHNLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVG 446
            |.|||..:...|:.:.|.:||..|||||..:|.|||:|||...|.|.|.|||||...:|...:||
Human   315 LLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVG 379

  Fly   447 AIGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYAD- 510
            |:|.|......:....:::.|....|.::|..|:|:|...|:.||||.|:   ..::.|:|||.
Human   380 AVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKI---TQLTPFNGYAGA 441

  Fly   511 KGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIITNCVG 575
            |..:|:|.||:||..||::|||||:::.|...:.||.||.||||||:||||||.||    .:.||
Human   442 KAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEV----ADTVG 502

  Fly   576 LEDCV----VYGVQIPHVEGKAGMAAI-VDPERKVDMDYLSVVLRGSLPPYARPLFIRLLDEIPR 635
            |.|.|    ||||.:|..||:.|||:| :....:.|...|...:...||.||||.|:|:.|.|..
Human   503 LVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEI 567

  Fly   636 TATFKLKKRELAKEAYDIGQLSDPIYYLNRDG-IYRPLSQE 675
            |.|||.:|..|.:|.::...:.|.:|:|:... :|.|::::
Human   568 TGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTED 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	219/533 (41%)
SLC27A2	NP_003636.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	224/560 (40%)