Protein Alignment Fatp3 and SLC27A4

DIOPT Version :9

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_005085.2
• Gene: SLC27A4 / 10999
• HGNCID: 10998
• Length: 643
• Species: Homo sapiens
• Alignment Length: 666
• Identity: 275/666 - (41%)
• Similarity: 393/666 - (59%)
• Gaps: 46/666 - (6%)

  Fly    43 LGTILLATVIFGAFC----WDN---ALASLTLGAVVALLLRNPTFVFALVMTASRDLKAFQRFVA 100
            ||..|:..::|....    |..   :|..|.||:      ....|:...:.|..||:  |...|.
Human     3 LGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGS------GGWRFIRVFIKTIRRDI--FGGLVL 59

  Fly   101 LNI-----YLLRKDRGGFTVARCFQDQARRRPKKTCFVMD--DRHLSFAEALEFSQKIAGYFSDR 158
            |.:     ..|::.|   ||...|....||.|.||..:.:  |.|.:|.:..|:|..:|.:...|
Human    60 LKVKAKVRQCLQERR---TVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQAR 121

  Fly   159 GLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIKVANAKALIVGSELLDV 223
            ||..||..|:.||.|.|:..:|||:::|||..||||:|||.::|||.:..:.|:||:.|||:...
Human   122 GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASA 186

  Fly   224 LVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPGAV-----DLVTALKTQKKLELPSAVCPGEA- 282
            :..           ::...|..:.........||||     .|...||...| .|||  ||.:.
Human   187 ICE-----------VHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPK-HLPS--CPDKGF 237

  Fly   283 RSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAI 347
            ..||.|:||||||||||||::.:.|:..|:|..||..:|..:|:|||.|||||:||.|||:|..:
Human   238 TDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCL 302

  Fly   348 LNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKHNLRLMYGNGLRPQI 412
            |:|.|||:||||||..||.||.::|||:.|||||||||||.......:.:|.:|:..|||||..|
Human   303 LHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSI 367

  Fly   413 WSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLKDS 477
            |:.|..||.||.:.|.|||||.|.:|.|..::|||.||.....|.:||::::|.:|.|.||::..
Human   368 WTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGP 432

  Fly   478 KGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILG 542
            .|.||.||||:.|.|||::..:..:..|.||.::||:.:|:.::||..||..:.:||::|.|.||
Human   433 DGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELG 497

  Fly   543 YFYFKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKAGMAAIVDPERKVDM 607
            |.||:|||||||||:||||:|.|||..::..:.:.|..||||::|..||:|||||:..|....|:
Human   498 YLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDL 562

  Fly   608 DYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKLKKRELAKEAYDIGQLSDPIYYLN-RDGIYRP 671
            :..:.||...||.||||:|:|||.|:.:|.|:|.:|.||.||.:|...:.||::||: :.|.|.|
Human   563 ERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVP 627

  Fly   672 LSQEQHELLRSGKAGL 687
            |.||.:..:::|:..|
Human   628 LDQEAYSRIQAGEEKL 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	262/607 (43%)
		hsFATP4_like	136..653	CDD:213305	236/522 (45%)
SLC27A4	NP_005085.2	hsFATP4_like	99..608	CDD:213305	236/522 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149113
Domainoid	1	1.000	79	1.000	Domainoid score	I8659
eggNOG	1	0.900	-	-		E1_KOG1179
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63225
OrthoDB	1	1.010	-	-		D390277at33208
OrthoFinder	1	1.000	-	-		FOG0000388
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100576
Panther	1	1.100	-	-	LDO	PTHR43107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2110
SonicParanoid	1	1.000	-	-		X222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.750