Protein Alignment nvy and runx1t1

DIOPT Version :9

• Sequence 1: NP_001261166.1
• Gene: nvy / 37886
• FlyBaseID: FBgn0005636
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_004915205.1
• Gene: runx1t1 / 100491944
• XenbaseID: XB-GENE-481238
• Length: 585
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 196/677 - (28%)
• Similarity: 296/677 - (43%)
• Gaps: 172/677 - (25%)

  Fly   104 HTSSSRSERDRERERERERERDRLCRTPPDSPPD---SSRSLAPRSPHSPLQLHQHPQRNASVSP 165
            |..|.....||..:|         | |.||||.|   .||...|..|..|..  |...|.:|.:|
 Frog     2 HFHSLPGPFDRTEKR---------C-TMPDSPVDVKTQSRLTPPTMPPPPTT--QGGPRTSSFTP 54

  Fly   166 --VVNGSSSGGGGVGSSGTSP---TPTPGSQHAASLAAAAAAAAAAHVEQARLVSKMRKFLGALV 225
              :.||:|.....:..:.:.|   :..|.|..::|||......|..    ||.:||:::||..|.
 Frog    55 TTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACG----ARQLSKLKRFLTTLQ 115

  Fly   226 QFSQELGQPEVCERVRALVLSLCSGSISVEEFRLALQEAINLPLRPYVVPLLKNSIALVQREILA 290
            ||..:: .||:.||||.|||.|.:.::::|||...||||.|.||||:|:|.||.::.|:|||:|.
 Frog   116 QFGNDI-SPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLH 179

  Fly   291 LARATNQSALQYVTNNEQAVMEFAPHGVASAEFGDIFIQLEAPTSNGSSAVFKRRSSDSMMEHG- 354
            .||...|:..||:..:||.:::.:.  .:..:..::.:.:   ..||     |||:.|...|:|
 Frog   180 CARLAKQNPAQYLAQHEQLLLDAST--TSPVDSSELLLDV---NENG-----KRRTPDRTKENGF 234

  Fly   355 ------------------------GHNGLQEWNEYMASGGAGYPPPPSKRLTLHPAHSVVAYGEY 395
                                    .:|||.     ....|..:|.||.      |.|       |
 Frog   235 DREPLHSEHPSKRPCTISPGQRYSPNNGLS-----FQPNGLPHPTPPP------PQH-------Y 281

  Fly   396 GVSSAEGLPSAAAFMQRD------ERDLR-MSEAQARHAAPPQRAGNPQPNPNAAAPGAPGAGGE 453
            .:..     .|.|...||      .|||| .:.....|....:...:.:......|
 Frog   282 RLDD-----MAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWA--------- 332

  Fly   454 EEWKNIHTMLNCISAMVDKTKRAITILQ-----------------------QRGIEPQHPNSGQE 495
            ||||::..:||||..||:||:|::|:|:                       ::|......:|.|:
 Frog   333 EEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGSSSSSSHSRQQ 397

  Fly   496 --VTPAAM-AELRRQTEEKVA------EFKRNAEDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQ 551
              |.|..: .|..|:...:.|      |..:.||:||.:|||||:.|:|:||..||.:|.|::|.
 Frog   398 SPVNPEPVPLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHEMITT 462

  Fly   552 ERLRMEKFFMEMSRHSSGERDLDNKSPSMASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSAS 616
            ||.:||:...|..|.::.:      :.|:.:.|..|:  :.||||||||:|||||||.||||.:.
 Frog   463 ERAKMERTVAEAKRQAAED------ALSVINQQEDSS--ESCWNCGRKASETCSGCNTARYCGSF 519

  Fly   617 CQYRDWDSHHQVCGNTRASELSAKHLHSASNLSLRNAMATRSPPTPNSAAHLQAAAAAAAAAAGA 681
            ||::||:.||.:||.|                    ..|.:...||       |.:::...::||
 Frog   520 CQHKDWEKHHHICGQT--------------------LQAQQQGETP-------AVSSSVTPSSGA 557

  Fly   682 REAVSAPVGG------PGAGIAVGTGA 702
            ...:..|...      ||....:.|.|
 Frog   558 GSPIDTPPAATPRSTTPGTPSTIETAA 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nvy	NP_001261166.1	TAFH	213..304	CDD:197785	43/90 (48%)
		NHR2	<454..>482	CDD:285941	15/50 (30%)
		zf-MYND	593..629	CDD:280009	25/35 (71%)
runx1t1	XP_004915205.1	TAFH	103..192	CDD:369407	42/89 (47%)
		NHR2	318..384	CDD:370124	16/74 (22%)
		NtpH	424..>490	CDD:225368	26/71 (37%)
		zf-MYND	496..532	CDD:366792	25/35 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D198762at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010