Protein Alignment nvy and cbfa2t3

DIOPT Version :10

• Sequence 1: NP_001261166.1
• Gene: nvy / 37886
• FlyBaseID: FBgn0005636
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_002933702.1
• Gene: cbfa2t3 / 100485526
• XenbaseID: XB-GENE-983684
• Length: 555
• Species: Xenopus tropicalis
• Alignment Length: 644
• Identity: 195/644 - (30%)
• Similarity: 301/644 - (46%)
• Gaps: 164/644 - (25%)

  Fly   132 PDSPPD-------SSRSLAPRSPHSPLQLHQHPQRNASVSP--VVNGSSSGGGGVGSSGTSPTPT 187
            ||||.|       |..::.|.||    .|.|...|::|.:|  ::||||       .|.|:....
 Frog     2 PDSPADVKTQTRTSPANMPPPSP----ALSQGTTRSSSFTPSTIMNGSS-------HSPTAINGA 55

  Fly   188 PGSQHAASLAAAAAAAAAAHVEQ------ARLVSKMRKFLGALVQFSQELGQPEVCERVRALVLS 246
            |.:.:..|...:|:::||...:|      ||.:||:::||..|.||..:: .||:.||||.|||.
 Frog    56 PSTPNGFSNGPSASSSAALTNQQLPPACGARQLSKLKRFLTTLQQFGSDI-SPEIGERVRTLVLG 119

  Fly   247 LCSGSISVEEFRLALQEAINLPLRPYVVPLLKNSIALVQREILALARATNQSALQYVTNNEQAVM 311
            |.:.::::|||...||||.|.||||:|:|.||.::.|:|||:|..||...||..||:..:||.::
 Frog   120 LVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQSPAQYLAQHEQLLL 184

  Fly   312 EFAPHGVASAEFGDIFIQLEAPTSNGSSAVFKRRSSDSMME------HGGH-------------- 356
            : |....:.::..::.:::   ..||     |||:.|...|      |..|
 Frog   185 D-ASSSSSPSDSPELLMEV---NENG-----KRRTPDRTKENAQEGVHPDHPAKRTCTTSPAQRF 240

  Fly   357 ---NGLQEWNEYMASGGAGYP-PPPSKRLTLHPAHSVVAYGEYGVSSAEGLPSAAAFMQRDERDL 417
               |||    .:..|.|..:| |||::...|                 |.:..|..:...:.|::
 Frog   241 SPSNGL----THPPSNGLPHPTPPPTQHYRL-----------------EDMVLAHHYRHTEPREV 284

  Fly   418 RMSEAQ-ARHAAPPQRAGNPQPNPNAAAPGAPGAGGEEEWKNIHTMLNCISAMVDKTKRAITILQ 481
            |....| |.|.....|....:              ..||||:::.:||||..||:||:|::|:|:
 Frog   285 RERHRQTAVHEVIDHRLTERE--------------WAEEWKHLNNLLNCIMDMVEKTRRSLTVLR 335

  Fly   482 Q----------------------------RGIEPQHPN--SGQEVTPAAMAE---LRRQTEEKVA 513
            :                            ...:.:|.|  |..|.:|.....   .|.|......
 Frog   336 RCQEADREELNHWIRRYSDAEDIKKTVSSASQQARHHNNTSSTESSPTEPTRDFLHRPQAGYMPE 400

  Fly   514 EFKRNAEDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQERLRMEKFFMEMSRHSSGERDLDNKSP 578
            |..|.||:||.:|||||:.|:|:||..||.:|.:::|.||.:||:...|..|.:|.:      :.
 Frog   401 EIWRKAEEAVNEVKRQAMSELQKAVSEAERKAHDLITVERAKMERALAEAKRQASED------AA 459

  Fly   579 SMASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSASCQYRDWDSHHQVCGNTRASELSAKHLH 643
            |:.:.|..|:  :.||||||||:|||||||.||||.:.||::||:.||.|||.:         ||
 Frog   460 SVINQQEDSS--ESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHVCGQS---------LH 513

  Fly   644 SASNLSLRNAMATRSPPTPNSAAHLQAAAAAAAAAAGAREAVSAPVGGPGAGIAVGTGA 702
            ..||:    ..|:.:|.||        .|:..|:::.:|.      |.|...:.:.|.:
 Frog   514 HPSNV----PPASTTPATP--------VASPTASSSVSRS------GTPATPLLLDTAS 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nvy	NP_001261166.1	TAFH	213..304	CDD:197785	44/90 (49%)
		NHR2	<454..>482	CDD:430219	15/27 (56%)
		zf-MYND	593..629	CDD:460312	25/35 (71%)
cbfa2t3	XP_002933702.1	TAFH	87..176	CDD:462195	43/89 (48%)
		NHR2	294..359	CDD:430219	17/78 (22%)
		TolA	403..>470	CDD:442298	28/74 (38%)
		zf-MYND	472..508	CDD:460312	25/35 (71%)