Protein Alignment nvy and cbfa2t2

DIOPT Version :10

• Sequence 1: NP_001261166.1
• Gene: nvy / 37886
• FlyBaseID: FBgn0005636
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001096296.1
• Gene: cbfa2t2 / 100124871
• XenbaseID: XB-GENE-950034
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 616
• Identity: 188/616 - (30%)
• Similarity: 284/616 - (46%)
• Gaps: 157/616 - (25%)

  Fly   132 PDSPPDSSRSLA-PRSPHSPLQLHQHPQRNASVSPVVNGSSSGGGGVGSSGTSPTPTPGSQHAAS 195
            |...|...||:| |.|.||....|..|..|.:.|| ...||:|              |.|..::|
 Frog    41 PPVNPGGPRSVAFPPSSHSNGINHSPPTLNGAPSP-PQRSSNG--------------PSSSSSSS 90

  Fly   196 LAAAAAAAAAAHVEQARLVSKMRKFLGALVQFSQELGQPEVCERVRALVLSLCSGSISVEEFRLA 260
            ||.....|...    .|.:||:::||..|.||..:: .||:.|:||.|||:|.:.::::|||...
 Frog    91 LANQQLPATCG----VRQLSKLKRFLTTLQQFGNDI-SPEIGEKVRTLVLALVNSTVTIEEFHCK 150

  Fly   261 LQEAINLPLRPYVVPLLKNSIALVQREILALARATNQSALQYVTNNEQAVMEFAPHGVASAEFGD 325
            ||||.|.||||:|:|.||.::.|:|||:|..|||..|:..||:..:|..::..:..  :.|:..:
 Frog   151 LQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHILLNTSTS--SPADSSE 213

  Fly   326 IFIQLEAPTSNGSSAVFKRRSSDSMMEHGGHNGLQEWNEYMASGGAGYPPPPSKRL-TLHPA--H 387
            :.:::     ||:.   ||.|.|...|:|            .......|.||.||: |:.||  |
 Frog   214 LLMEV-----NGNG---KRHSPDRREENG------------CEREPALPEPPVKRVCTISPAPRH 258

  Fly   388 S-------VVAYGEYGVS-------SAEGLPSAAAFMQR-----DERDLRMSEAQARHAAPPQRA 433
            |       |.:...:..:       |.|.:||:..:..:     :.||:|     .||
 Frog   259 SPALSLPIVNSTSHFHPTPPPLQHYSLEDIPSSQLYRDQLSKIAEHRDIR-----DRH------- 311

  Fly   434 GNPQPNPNAAAPGAPGAGGE--------------------EEWKNIHTMLNCISAMVDKTKRAIT 478
                        .:.|..|.                    ||||::...||||..||:||:|::.
 Frog   312 ------------HSSGVNGNLNNGYQEELVDHRLTEREWAEEWKHLDHALNCIMEMVEKTRRSMA 364

  Fly   479 ILQ-----------------------QRGIE---PQH-PNSGQEVTPAAMAEL--RRQTEEKVAE 514
            :|:                       ::|.|   .|| |.|....|..::.:.  |..|.....|
 Frog   365 VLRRCQEVDRDELNYWKRRFNESNEIRKGSEHLSRQHSPTSTDSGTSDSIRDFGSRTGTGYVTDE 429

  Fly   515 FKRNAEDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQERLRMEKFFMEMSRHSSGERDLDNKSPS 579
            ..|.||:||.:|||||:.|:|:||..||.:|.|::..||.|||:...:..|.::.:..|
 Frog   430 IWRKAEEAVNEVKRQAMSEVQKAVSEAEQKAFEMIASERARMEQTIADTKRRAAEDAFL------ 488

  Fly   580 MASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSASCQYRDWDSHHQVCG---NTRASELSAKH 641
            :.:.|..|.  :.||||||||:|||||||:||||.:.||::||:.||::||   :|:...|:...
 Frog   489 VVNEQEEST--ESCWNCGRKASETCSGCNIARYCGSFCQHKDWEKHHRICGQGIHTQTKPLTPTR 551

  Fly   642 --LHSASNLSL------RNAMATRSPPTPNS 664
              :..||:..|      |::.||....||.|
 Frog   552 SLIPKASDPVLLSPTLERSSSATSRSSTPAS 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nvy	NP_001261166.1	TAFH	213..304	CDD:197785	43/90 (48%)
		NHR2	<454..>482	CDD:430219	14/50 (28%)
		zf-MYND	593..629	CDD:460312	25/35 (71%)
cbfa2t2	NP_001096296.1	TAFH	104..193	CDD:462195	42/89 (47%)
		NHR2	325..391	CDD:430219	14/65 (22%)
		NtpE	426..>482	CDD:441000	25/55 (45%)
		zf-MYND	500..536	CDD:460312	25/35 (71%)