Protein Alignment hspa5 and Hsc70-4

DIOPT Version :10

• Sequence 1: NP_998223.1
• Gene: hspa5 / 378848
• ZFINID: ZDB-GENE-031001-11
• Length: 650
• Species: Danio rerio
• Sequence 2: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 620
• Identity: 397/620 - (64%)
• Similarity: 501/620 - (80%)
• Gaps: 6/620 - (0%)

Zfish    24 SVGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPEN 88
            |....:|||||||||||||:::|:|||||||||||.||||||| |:.|||||||||||:..||..
  Fly     2 SKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAF-TDTERLIGDAAKNQVAMNPTQ 65

Zfish    89 TVFDAKRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKE 153
            |:|||||||||.:.|::||.|:|::||:|:....||.|::.. ..:.|||.|||||:||||||||
  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTY-KDEKKTFFPEEISSMVLTKMKE 129

Zfish   154 TAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRD-GEKN 217
            ||||||||.||:||:||||||||:||||||||||||||||:|||||||||||||||||:. ||:|
  Fly   130 TAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERN 194

Zfish   218 ILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRA 282
            :|:|||||||||||:|:||:|:|||.:|.|||||||||||.|::.||::.:|:|..||:..:.||
  Fly   195 VLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRA 259

Zfish   283 VQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDS 347
            :::||...|:|||.||:..||.|||:|.|||.||..::|||:|||||.|||||||.||:|.|.|:
  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324

Zfish   348 DPKKPDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGE--EETG 410
            ...|..|.:||||||||||||:|:|:::.|||||.::.|||||||||||||||.:|.|:  :|..
  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389

Zfish   411 DLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNH 475
            ||:||||.||:|||||.||||:.||.|||.:|||::|.|:|.|||||.|.|:||||||.:||||:
  Fly   390 DLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN 454

Zfish   476 LLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMV 540
            |||.|:|:||||||||||||||||:||.||||.|||.::.|..:||||||||:.||:.|||||||
  Fly   455 LLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMV 519

Zfish   541 NEAERFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWLEA 605
            ||||::.:||:|.||.|.::|.||||.:::|..: |::.|..|:|..|:..|.....|.|:||:|
  Fly   520 NEAEKYRNEDEKQKETIAAKNGLESYCFNMKATL-DEDNLKTKISDSDRTTILDKCNETIKWLDA 583

Zfish   606 HQDADLEEFQAKKKELEEVVQPIVSKLYGSAGGPP 640
            :|.||.||::.::||||.|..||::|||..||.||
  Fly   584 NQLADKEEYEHRQKELEGVCNPIITKLYQGAGFPP 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hspa5	NP_998223.1	PTZ00009	29..641	CDD:240227	396/615 (64%)
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	392/612 (64%)