Protein Alignment CG3376 and PPN1

DIOPT Version :10

• Sequence 1: NP_001246491.1
• Gene: CG3376 / 37884
• FlyBaseID: FBgn0034997
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_010740.3
• Gene: PPN1 / 852063
• SGDID: S000002860
• Length: 674
• Species: Saccharomyces cerevisiae
• Alignment Length: 543
• Identity: 129/543 - (23%)
• Similarity: 198/543 - (36%)
• Gaps: 144/543 - (26%)

  Fly   274 EVIFPPVPKPPRLP----DLPIPMEAAPFFKVLHISDTHYDPHYAEGSNADCNEPLCCRLSSGRP 334
            ::.|..:...||.|    |:....|.....:.|||:|.|.||:|.|||:.|.   :|   .:|:|
Yeast    66 DIEFTRLGLTPREPVIIKDVKTGKERKLHGRFLHITDIHPDPYYVEGSSIDA---VC---HTGKP 124

  Fly   335 ATPNAAAGKWGDYRK-CDTPKRTVDHMLSHIAETHKD-IDYILWTGDLPPHDVWNQTKEENLA-- 395
            :.....|.|:|.... ||:|...::..|..|.|..:| ||:::||||...||  |..|.....
Yeast   125 SKKKDVAPKFGKAMSGCDSPVILMEETLRWIKENLRDKIDFVIWTGDNIRHD--NDRKHPRTEAQ 187

  Fly   396 ------IIKDTVKQMVEMFPG----------VPIFPALGNHESAPVNSFP--PPYVNQVDISISW 442
                  |:.|   :|.|:|..          |.:.|:|||::..|.|.|.  |....:....|
Yeast   188 IFDMNNIVAD---KMTELFSAGNEEDPRDFDVSVIPSLGNNDVFPHNMFALGPTLQTREYYRI-- 247

  Fly   443 LYDELDIQWRRWLPQSVTHTVRRGAFYSVLVRPG-FRIISLNMNY----------CNNKNWWLLL 496
                    |:.::||....|..|.|.:...|.|| ..::|:|..|          ||:|.
Yeast   248 --------WKNFVPQQQQRTFDRSASFLTEVIPGKLAVLSINTLYLFKANPLVDNCNSKK----- 299

  Fly   497 NSTDPATE-LQWFIYELQSAEFSNEKVHVIGHIPP-------GHSDCLKVWSRNFYKIISRYEST 553
               :|..: |.||.|.|:.......||.:.||:||       ...|...:|:.       .|...
Yeast   300 ---EPGYQLLLWFGYVLEELRSRGMKVWLSGHVPPIAKNFDQSCYDKFTLWTH-------EYRDI 354

  Fly   554 VTAQFYGHTHYDEFEMFYDPHDLNHPNGIAYIGPSV--SPYYDLNPGYRIYYVD--GDHDATTRL 614
            :....|||.:.|.|    .|.|          |...  |....:....|:...:  .:.|..|.|
Yeast   355 IIGGLYGHMNIDHF----IPTD----------GKKARKSLLKAMEQSTRVQQGEDSNEEDEETEL 405

  Fly   615 --VIDH-----ESWIMNLKEANLYGYPIWYKLYTARAAYNMKALRPSDWNNL--LNELTNNQELF 670
              ::||     |.::|..|.:|...|     :.|.|..|..|.     ||.|  ::|.....|..
Yeast   406 NRILDHAMAAKEVFLMGAKPSNKEAY-----MNTVRDTYYRKV-----WNKLERVDEKNVENEKK 460

  Fly   671 ELYYKYYWKNSPARPTCDAECKKRLICDCRSGRSHDRKHFCAEVESKIDEESSKSWKSWFYK--G 733
            :...|...|..|.       .:|.||          .::....:...:....:.|::.|.|.  .
Yeast   461 KKEKKDKKKKKPI-------TRKELI----------ERYSIVNIGGSVIPTFNPSFRIWEYNITD 508

  Fly   734 LTNSAEDRTEEPAPTTDGYGPFD 756
            :.|.:.....|       |.|:|
Yeast   509 IVNDSNFAVSE-------YKPWD 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3376	NP_001246491.1	SapB	186..258	CDD:214797
		MPP_ASMase	301..600	CDD:277321	89/341 (26%)
		ASMase_C	584..697	CDD:466022	27/125 (22%)
PPN1	NP_010740.3	MPP_ASMase	97..375	CDD:277321	88/327 (27%)