DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3376 and CG32052

DIOPT Version :9

Sequence 1:	NP_001246491.1	Gene:	CG3376 / 37884	FlyBaseID:	FBgn0034997	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001303410.1	Gene:	CG32052 / 326184	FlyBaseID:	FBgn0044328	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	115/477 - (24%)
Similarity:	178/477 - (37%)	Gaps:	111/477 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 HISDTHYDPHYAEGSN--ADCNEPLCCRLSSGRPATPNAAA----GKWGDYRKCDTPKRTVDHML 361
            ||||.|.|..|:...:  ..|.|  ..|..||..|  |:||    |.:|.| .||:|.|.::..:
  Fly    30 HISDLHLDTLYSTQGDIYRSCWE--LARSVSGSNA--NSAASEPPGPFGHY-NCDSPWRLIESAV 89

  Fly   362 SHI-AETHKDIDYILWTGDLPPHDVWNQTKEENLAIIKDTVKQMVEMFPGVPIFPALGNHESAPV 425
            ..: |:...:::::|||||...|.....::::...|:::..:.:...|....|||.|| ||..
  Fly    90 KTMKAKQGDNVEFVLWTGDALSHSAQPLSEQKQHEILRNITELLGRSFSSQFIFPVLG-HEDG-- 151

  Fly   426 NSFPPPYVNQVDISISWLYDELDIQWRRWLPQSVTHTVRRGAFYSV-LVRPGFRIISLNMNYCNN 489
                           |..|..|...||.|||.....|..:|.:||: ..:...||::||.|:..
  Fly   152 ---------------SGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQTKSRLRIVALNTNFMR- 200

  Fly   490 KNWWLLLNSTDPATEL-----------------------------QWFIYE--LQSAEFSNEKVH 523
                 |....||...|                             ||...|  |..::...|.|:
  Fly   201 -----LDPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVLTKSKEKQETVY 260

  Fly   524 VIGHIPPG---------HSDCLKVWSRN---FYKIISRYESTVTAQFYGHTHYDEFEMFYDPHDL 576
            ::||:|||         |:. |....||   :..::.|:...:..||:||.|.|.|.:.||..
  Fly   261 IVGHMPPGVDERHLGTQHNQ-LTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDTFRLIYDAK-- 322

  Fly   577 NHPNGIAYIGPSVSPY-----YDLNPGYRIYYVDGDHDATTRLVIDHESWIMNLKEANLYGYPIW 636
            .:|.....|.||:.|.     ...||..|:|    ..|..:..|:|:..:.::|..||....|.|
  Fly   323 GNPISWLMIAPSIVPRKAGIGSSNNPALRLY----KFDTGSGQVLDYTQFWLDLPLANRANEPTW 383

  Fly   637 YKLYTARAAYNMKALRPSDWNNLLNELTNNQELFELYYKYYWKNS---PARPTCDAECKKRLICD 698
            ...|.....|.:..:.....:|.....|...  ...:.:|:..|:   .:...|...|.
  Fly   384 QPEYNLTHYYALPEISAVALHNFAERFTGTD--LSWFTRYHRANAVRYHSGSACPGLCM------ 440

  Fly   699 CRSGRSHDRKHFCAEVESKIDE 720
                    ..|:||......||
  Fly   441 --------LNHYCAITRLDYDE 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3376	NP_001246491.1	SapB	186..258	CDD:214797
		Metallophos	299..563	CDD:278574	80/310 (26%)
		MPP_ASMase	301..600	CDD:277321	92/352 (26%)
CG32052	NP_001303410.1	MPP_ASMase	28..351	CDD:277321	92/352 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	1	1.000	-	-		otm46555
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R975
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.880