Protein Alignment CG3376 and asm-2

DIOPT Version :9

• Sequence 1: NP_001246491.1
• Gene: CG3376 / 37884
• FlyBaseID: FBgn0034997
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_509894.2
• Gene: asm-2 / 181323
• WormBaseID: WBGene00000212
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 216/597 - (36%)
• Similarity: 313/597 - (52%)
• Gaps: 51/597 - (8%)

  Fly   146 WYDVAGGDGLVYPPFVDKALKLLNLKQVAFEIENSVMSKVTCTACRAGAGMLQHQIQSGKTDAEL 210
            |.:..|.:..|.||   |...|...|:...|.||..||.:.||....|   :|..|....||.|:
 Worm    37 WTNARGNEAAVPPP---KYKMLRYAKKAINEPENRKMSCLFCTFAVDG---VQALIAQNSTDNEI 95

  Fly   211 IRMITDYCTNLNIQSARVCQGVAQLFGSELIYVLKRVNLSPDELC-SFVIGDGCADVYNPY-HEW 273
            ...:.:.|...:::...||:.:...|..|:::||:|...:|:|:| :|:...|.:|  .|. |.|
 Worm    96 AAFLVNLCDLFDVEQPHVCKNIIYAFKDEVVFVLERSVFTPEEICGAFIANCGHSD--KPLTHMW 158

  Fly   274 EVIFP---PVPKP-PRLPDLPIPMEAAPFFKVLHISDTHYDPHYAEGSNADC-------NEPLCC 327
            .:..|   |..|| |::||      ..|.|||||:||.|.|..|..|:.|.|       ...:||
 Worm   159 NITIPGGKPPIKPWPKIPD------NKPTFKVLHLSDIHIDHQYVVGTEAYCQLDSALGTYAMCC 217

  Fly   328 R----LSSGRPATPN-----AAAGKWGDYRKCDTPKRTVDHMLSHIAETHKDIDYILWTGDLPPH 383
            |    .|.|.|....     ..||.||....||.|.:|.:..:.||::|.||:|||:.|||...|
 Worm   218 RDYSQDSQGAPTNLKDKPIYVPAGPWGMPYLCDLPYQTFESAMKHISKTFKDLDYIIITGDFEAH 282

  Fly   384 DVWNQTKEENLAIIKDTVKQMVEMFPGVPIFPALGNHESAPVNSFPPPYVNQVDI-SISWLYDEL 447
            |.|:.|::.....:.:.....:|.|||||::.::||||..|.::..|..:.:.|. ...|||..:
 Worm   283 DSWDYTEDLTRENMNNMTNVFLEYFPGVPVYVSIGNHEGVPQDAMAPHTMPEYDTRGPQWLYKIM 347

  Fly   448 DIQWRRWLPQSVTHTVRRGAFYSVLVRPGFRIISLNMNYCNNKNWWLLLNSTDPATELQWFIYEL 512
            ...|..|:||....||:..|.|:|..:||.::||||..||:..|::|.:|..||...|:|.|.||
 Worm   348 SEMWSHWIPQEALDTVQYRASYAVYPKPGLKLISLNTIYCSEFNFYLYVNEVDPDATLEWLIEEL 412

  Fly   513 QSAEFSNEKVHVIGHIPPGHSDCLKVWSRNFYKIISRYESTVTAQFYGHTHYDEFEMFYDPHDLN 577
            |.:|...|.||:|.|||||.:.|||.||.||::|:.|||:|:...||||||||:|.::||..|.|
 Worm   413 QDSENKGELVHIISHIPPGDNYCLKGWSWNFFEIVKRYENTIAQMFYGHTHYDQFMVYYDMDDPN 477

  Fly   578 -HPNGIAYIGPSVSPYYDLNPGYRIYYVDGDHDATTRLVIDHESWIMNLKEANLYG-YPIWYKLY 640
             .|....:|.||::.|..|||.||||.:||.::..|..|.|.:::..|:.|||:.. .|.|...|
 Worm   478 RRPFHFNWISPSLTTYDWLNPAYRIYEIDGGYEGATYTVKDAKTYFANVTEANMKNKEPEWVLSY 542

  Fly   641 TARAAYNMKALRPSDWNNLLNELTNNQELF----ELYYKYYWKNSPARPTC--DAECKKRLICDC 699
            ..|..|.|....|..|::|.::|..|..||    .|||:.::.|.     |  |.:|:...:||.
 Worm   543 DTREHYQMADFSPQSWSDLSDKLWTNTTLFRDYVRLYYRNHYNNE-----CYTDYKCRYTFVCDI 602

  Fly   700 RSGRSHDRKHFC 711
            :.|||:| :.||
 Worm   603 KKGRSYD-ESFC 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3376	NP_001246491.1	SapB	186..258	CDD:214797	19/72 (26%)
		Metallophos	299..563	CDD:278574	112/280 (40%)
		MPP_ASMase	301..600	CDD:277321	127/316 (40%)
asm-2	NP_509894.2	SapB	70..143	CDD:214797	21/75 (28%)
		SapB_1	72..106	CDD:282970	9/36 (25%)
		MPP_ASMase	184..501	CDD:277321	127/316 (40%)
		CpdA	251..555	CDD:224327	123/303 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160974
Domainoid	1	1.000	234	1.000	Domainoid score	I1340
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H457
Inparanoid	1	1.050	379	1.000	Inparanoid score	I1200
Isobase	1	0.950	-	0.543564	Normalized mean entropy	S3573
OMA	1	1.010	-	-		QHG53732
OrthoDB	1	1.010	-	-		D1142100at2759
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	1	1.000	-	-		otm14174
orthoMCL	1	0.900	-	-		OOG6_101180
Panther	1	1.100	-	-	LDO	PTHR10340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R975
SonicParanoid	1	1.000	-	-		X1866
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790