Protein Alignment CG13575 and Tacr3

DIOPT Version :10

• Sequence 1: NP_611903.1
• Gene: CG13575 / 37883
• FlyBaseID: FBgn0034996
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_067357.1
• Gene: Tacr3 / 21338
• MGIID: 892968
• Length: 452
• Species: Mus musculus
• Alignment Length: 521
• Identity: 106/521 - (20%)
• Similarity: 193/521 - (37%)
• Gaps: 158/521 - (30%)

  Fly    16 EWAFAQHG---EATPIPSIQPYPGVFVGDLSQLNRFKRHA-----FSAVVGTLFVLAFCGNLSTL 72
            ||...|.|   .|..:|.....|.....:|:  |:|.:.:     :|...|.:..:|..|||..:
Mouse    32 EWLALQAGNFSSALGLPVTSQAPSQVRANLT--NQFVQPSWRIALWSLAYGLVVAVAVFGNLIVI 94

  Fly    73 Y-VNSRRKLRPFFRACLISLACSDLVSSIFCT-VSYMAQFQAQYLQLWTIGGFMCKFVPFITTTS 135
            : :.:.:::|......|::||.||...:.|.| |:::....::    |..|...|:|..|...|:
Mouse    95 WIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLVNFIYGVHSE----WYFGANYCRFQNFFPITA 155

  Fly   136 VLSGSLTLVAIALDRYLAVMRPVLGFWSPDKRFSTLSMLLIWACSIGSSGPLLGIYDYRKIYLLD 200
            |.:...::.|||:|||:|::.|:      ..|.|..:..::    |||            |::|
Mouse   156 VFASIYSMTAIAVDRYMAIIDPL------KPRLSATATKIV----IGS------------IWIL- 197

  Fly   201 VEDSSEESEEVVTAVPEELVVTELEMV---HMCLA----GDHDVGLYYVILFTLIF-LPCIVSFL 257
                     ..:.|.| :.:.::::::   .:|..    |......|::|:..|:: .|.::..:
Mouse   198 ---------AFLLAFP-QCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGV 252

  Fly   258 WLNAVIARQLWLRRHYHQEQQEQHQEPKEGQFKTMANGGDLLMPSTLVSAMGVAVPFALDNTPLP 322
             ...::...||                          ||::
Mouse   253 -TYTIVGITLW--------------------------GGEI------------------------ 266

  Fly   323 PKSTVNAPGKKTTAAALAREARHRKMVVVVLLMMAVFICLRLPAWVFLIMRLYGSYSEPIDW--- 384
            |..|.:...::..|        .||:|.::::::..|....||..|:.|  |...|.:...|
Mouse   267 PGDTCDKYHEQLKA--------KRKVVKMMIIVVVTFAICWLPYHVYFI--LTAIYQQLNRWKYI 321

  Fly   385 -LLYFSFGILNLFSCALNPIFYTFLTQTIRTLTLVKHKIQGFLGCPPGKVPDGMPTDQMDKSGCC 448
             .:|.:...|.:.|...|||.|..|.:..|    ...| :.|..||..:|..   .|:::..
Mouse   322 QQVYLASFWLAMSSTMYNPIIYCCLNKRFR----AGFK-RAFRWCPFIQVSS---YDELELK--- 375

  Fly   449 CGLRPPTFTWRCHPSRDRA--------AATVIRDVDQPDPPSDQ-----VQPDPS----SLRRFL 496
                    |.|.||:|..:        :.||:.|..:.||....     |..|||    |.|.|.
Mouse   376 --------TTRFHPTRQSSLYTVSRMESVTVLYDPSEGDPAKSSRKKRAVPRDPSANGCSHREFK 432

  Fly   497 S 497
            |
Mouse   433 S 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13575	NP_611903.1	7tm_classA_rhodopsin-like	53..408	CDD:410626	70/368 (19%)
		TM helix 1	53..77	CDD:410626	6/24 (25%)
		TM helix 2	84..113	CDD:410626	8/29 (28%)
		TM helix 3	125..155	CDD:410626	12/29 (41%)
		TM helix 4	168..187	CDD:410626	4/18 (22%)
		TM helix 5	237..262	CDD:410626	4/25 (16%)
		TM helix 6	343..373	CDD:410626	8/29 (28%)
		TM helix 7	384..408	CDD:410626	8/27 (30%)
Tacr3	NP_067357.1	7tmA_NKR_NK3R	73..354	CDD:320669	72/382 (19%)
		TM helix 1	74..100	CDD:320669	6/25 (24%)
		TM helix 2	107..133	CDD:320669	8/25 (32%)
		TM helix 3	145..175	CDD:320669	12/29 (41%)
		TM helix 4	186..207	CDD:320669	7/47 (15%)
		TM helix 5	231..260	CDD:320669	4/29 (14%)
		TM helix 6	279..309	CDD:320669	9/39 (23%)
		TM helix 7	322..347	CDD:320669	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..452		11/33 (33%)