DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13575 and R13H4.7

DIOPT Version :9

Sequence 1:	NP_611903.1	Gene:	CG13575 / 37883	FlyBaseID:	FBgn0034996	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001256380.1	Gene:	R13H4.7 / 187874	WormBaseID:	WBGene00011265	Length:	347	Species:	Caenorhabditis elegans

Alignment Length:	270	Identity:	51/270 - (18%)
Similarity:	81/270 - (30%)	Gaps:	113/270 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 VGLYYVILFTLIFLPCIVSF-LWLNAVIARQ------------------LWLRRHYHQ-----EQ 277
            ||..::|...|..:..::.| :|...||..|                  .|....||.     .:
Worm    38 VGFRFLISQALTDILLMIQFGIWPGIVILTQNEIINESWRWNIHIYLDFTWWAMVYHYTVIAWSR 102

  Fly   278 QEQHQEPKEGQFKTMANGGDLLMPSTLVSAMGVAVPF---ALDN---------TPL---PPKSTV 327
            ....|.|  ..|:|:.:|         .|.|..|:|:   .|.:         |||   |.:..:
Worm   103 LAAVQWP--NWFRTLPHG---------TSIMICAIPWFTGLLQSLVEHQFDWFTPLFYSPTRYGM 156

  Fly   328 NAPGKKTTAAALAREARHRKMVVVVLLMMAVFICLRLPAWVFLI-----------MRLYGSYSE- 380
            ::..:|...:.    .....||..|:||:..|     |.:|..:           |:|...||.
Worm   157 HSDWEKYELSG----TNTYYMVCNVILMVVPF-----PLYVLALAVLFQRQTSRNMQLRSKYSHA 212

  Fly   381 PIDWLLY-----------------------FSFGILNLFSCA-------------------LNPI 403
            ||....|                       |..|.:.:..|:                   :||:
Worm   213 PISTSSYAAQQRQLSIETRLLVPCIINTILFVVGQVFISQCSKHGKWMNWAVMVVFATNSFVNPL 277

  Fly   404 FYTFLTQTIR 413
            .|.|.:..||
Worm   278 LYLFFSSVIR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13575	NP_611903.1	7tm_1	67..>188	CDD:278431
R13H4.7	NP_001256380.1	7tm_GPCRs	6..283	CDD:333717	49/264 (19%)
		TM helix 1	6..29	CDD:320095
		TM helix 2	40..63	CDD:320095	4/22 (18%)
		TM helix 3	79..100	CDD:320095	3/20 (15%)
		TM helix 4	122..143	CDD:320095	4/20 (20%)
		TM helix 5	169..192	CDD:320095	8/27 (30%)
		TM helix 7	258..283	CDD:320095	4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166769
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930