Protein Alignment CG13575 and ckr-2

DIOPT Version :10

• Sequence 1: NP_611903.1
• Gene: CG13575 / 37883
• FlyBaseID: FBgn0034996
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001367973.1
• Gene: ckr-2 / 175341
• WormBaseID: WBGene00021439
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 89/489 - (18%)
• Similarity: 173/489 - (35%)
• Gaps: 152/489 - (31%)

  Fly    44 QLNRFK----RHAFSAVVGTLFVLAFCGNLSTLYV-NSRRKLRPFFRACLISLACSDLVSSIFCT 103
            ::.||:    .:..:.....:|:|:..||...|.| ..:|.:|......|::||.||::.|:.|.
 Worm    50 EICRFRGTTENYTIAVTFFMIFLLSVVGNSVVLIVIIKQRAMRSITNIYLMNLAASDMMLSVVCM 114

  Fly   104 VSYMAQFQAQYLQLWTIGGFMCKFVPFITTTSVLSGSLTLVAIALDRYLAVMRPVLG-FWSPDKR 167
            ...:.   :..:..|..|.:|||.:.::....|.:.:.||..||.:||.|:.:|:.. .|  ..|
 Worm   115 PPTLV---SMVMNCWMFGNYMCKILAYLQPVVVTASAYTLAVIAFERYFAICKPLHSRIW--QTR 174

  Fly   168 FSTLSML-LIWACSIGSSGPLLGIYDYRKIYLLDVEDSSEESEEVVTAVPEELVVTELEMVHMCL 231
            ....:|: |:|..:|.::..:|.:|: ::.|          |....|..|          :|..:
 Worm   175 SHAYAMITLVWVIAIAANILMLFMYE-QQTY----------SSNGYTCAP----------IHPPI 218

  Fly   232 AGDHDVGLYYVILFTLIFLPCIVSFLWLNAVIARQLWLRRHYHQEQQEQHQEPKEGQFKTMANGG 296
            .  |.....|:.:..|:....:::.|:.|.:.:.:..::................|. |.:.:..
 Worm   219 Y--HFAYQVYMTVVLLVIPLVVMAGLYGNVITSLKSGIKLEIASVDPPLATATTTGA-KNLGSHS 280

  Fly   297 D---LLMPSTLVSAMGVA--------VPFALDN--------TPLPPKSTVN--------APGK-- 332
            |   ||:.:.||.:..:|        ..|:.:|        ||.||....|        .|||
 Worm   281 DSAHLLLNNVLVGSSQLARATSCIALNTFSCNNTTNPFSTLTPPPPIQQKNRSKPQLLQLPGKID 345

  Fly   333 ----------------------------------------------------------------- 332
                                                                             
 Worm   346 NFEEFRLQCLSDCRSDGVLFPPPAIVASMTDEQKLSFWNKLSNKLTFSQQDKTVQHPNFGHRKSD 410

  Fly   333 -------------KTTAAALAREARHRKMVVVVLLMMAVFICLRLPAWVFLIMRLYGSYSEPIDW 384
                         .|..:|:|:: |..||::||::   :|.|...|::::.::.:.|...:.::.
 Worm   411 TSICLENPSLRSTHTQKSAMAKQ-RVIKMLIVVVI---IFFCCWTPSYIWWLLLIAGDSFQSLNL 471

  Fly   385 LLYFS-----FGILNLFSCALNPIFYTFLTQTIR 413
            .::.|     ..:|...|...|||.|.||.:..|
 Worm   472 SVWNSDINTFITLLTYISSCTNPITYCFLNKKFR 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13575	NP_611903.1	7tm_classA_rhodopsin-like	53..408	CDD:410626	84/469 (18%)
		TM helix 1	53..77	CDD:410626	6/24 (25%)
		TM helix 2	84..113	CDD:410626	7/28 (25%)
		TM helix 3	125..155	CDD:410626	10/29 (34%)
		TM helix 4	168..187	CDD:410626	4/19 (21%)
		TM helix 5	237..262	CDD:410626	4/24 (17%)
		TM helix 6	343..373	CDD:410626	8/29 (28%)
		TM helix 7	384..408	CDD:410626	7/28 (25%)
ckr-2	NP_001367973.1	7tmA_CCKR-like	61..508	CDD:320124	87/478 (18%)
		TM helix 1	62..88	CDD:320124	6/25 (24%)
		TM helix 2	95..121	CDD:320124	7/28 (25%)
		TM helix 3	133..163	CDD:320124	10/29 (34%)
		TM helix 4	177..195	CDD:320124	4/17 (24%)
		TM helix 5	220..245	CDD:320124	4/24 (17%)
		TM helix 6	430..460	CDD:320124	9/33 (27%)
		TM helix 7	476..501	CDD:320124	8/24 (33%)