Protein Alignment nord and Ndnf

DIOPT Version :10

• Sequence 1: NP_611900.1
• Gene: nord / 37882
• FlyBaseID: FBgn0050418
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_765987.2
• Gene: Ndnf / 68169
• MGIID: 1915419
• Length: 568
• Species: Mus musculus
• Alignment Length: 618
• Identity: 133/618 - (21%)
• Similarity: 224/618 - (36%)
• Gaps: 173/618 - (27%)

  Fly    65 QKCPSL--QRYRKMLKDFDDLED-------------LYVDVPVHIALAERQRKRFVLNLNDSTPL 114
            ||.|:.  :.::..::|.:...|             |:.|.|         |:.|.:...|:|||
Mouse    20 QKLPTRDEELFQMQIRDKEFFHDSSVIPDGAEVSSYLFRDTP---------RRYFFMVEEDNTPL 75

  Fly   115 TIRFS---APVGRKMYYNQ---------TGNP------------LRPAAVAPGPGVAVGSLVLPC 155
            ::..:   ||:..|:...:         :|:|            :....:....|..|...:...
Mouse    76 SVTVTPCDAPLEWKLSLQELHEGSSADGSGDPELLDQQKQQMTDVEGTELFSYKGNDVEYFLSSS 140

  Fly   156 ALRGQYDLFVLARHSGA-LKVDALAEHPQHD--WPLLNATHRIAIRTQNRVRKREMIVKWERS-- 215
            :..|.|.|.:|:..... .||.|... |:.|  :|.|....|:.:.:..|.   .:.:.|:.|
Mouse   141 SPSGLYQLELLSTEKDTHFKVYATTT-PESDQPYPELPYDPRVDVTSFGRT---TVTLAWKPSPT 201

  Fly   216 -KFDFHVMHYCLVIQRLSMDTPRMIFTNFCQA-VSAYTDQQPMTPSCAAGGPLEGI--------- 269
             ......:.||:||.:      ...|.:.|.| .....|...|.      .|..|:
Mouse   202 ASILKQPIEYCVVINK------EHNFKSLCAAETKMNADDAFMV------APKPGLDFNPFDFAH 254

  Fly   270 WGAPPQ---RERRL--------------NPRQNVHIVCTGKRRQQLLRRLLPRSSYHLDLFGIHQ 317
            :|.|..   ::|.|              .|:.::..:|.|.:....:..|.|.:.|:.|:|.:
Mouse   255 FGFPTDNLGKDRSLLAKPSPKVGRHVYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMV-- 317

  Fly   318 GRQNLTLRLASSQVN-FNRTQPLALKQQALMQLKIG-------GQHGKQVYSFKVPQTTRQLGEP 374
               |....::::.|. |.||:..|  :|..::||.|       .:.||:...| .|.::.| ...
Mouse   318 ---NTNTNMSTAYVGAFVRTKEEA--KQKTVELKDGRVTDVFVKRKGKKFLRF-APVSSHQ-KVT 375

  Fly   375 FMRHLLIPCSGSEIR----------VKLLRQRSEVGKTEAFYSPTYIRQKGVLPGERYLMRFEPS 429
            |..|..:.....::|          |:.:||....||.:..|   .||.||...|
Mouse   376 FFIHSCMDAVQVQVRRDGRLLLSQNVEGIRQFQLRGKPKGKY---LIRLKGNRKG---------- 427

  Fly   430 NDDEALRAQKVMVALSSEALFRDLPELPQNTTV--FNVRTRCSRATIAWNGSPDERELSYCIIVF 492
                   |.|:.:..::.......|.||::|.:  |:....||..|:||.|:.:.|:  :||.
Mouse   428 -------ASKLKILATTRPSKHAFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERRK--FCIY-- 481

  Fly   493 NLPQRNRSVVDFTNYCMDFVPKRVMQYRYF--------EWMTCR--ERQQSPDNIETETILNLMP 547
                  |..|| .||..|  .||..|.:..        |.:.|:  ..|.....:.||||.:|.|
Mouse   482 ------RKEVD-GNYSED--QKRREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQP 537

  Fly   548 GSSYL--VYVTANLSMGKPLPYQALTLHMASQC 578
            |.|||  |||..:  .|..:.||:..:.....|
Mouse   538 GKSYLLDVYVVGH--GGHSVKYQSKIVKTRKVC 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nord	NP_611900.1	NDNF	208..333	CDD:462981	27/155 (17%)
		NDNF_C	418..568	CDD:466079	43/163 (26%)
Ndnf	NP_765987.2	NDNF	192..335	CDD:462981	29/159 (18%)
		NDNF_C	394..568	CDD:466079	55/208 (26%)