Protein Alignment nord and ndnf-1

DIOPT Version :10

• Sequence 1: NP_611900.1
• Gene: nord / 37882
• FlyBaseID: FBgn0050418
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_500282.2
• Gene: ndnf-1 / 177083
• WormBaseID: WBGene00021893
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 132/644 - (20%)
• Similarity: 230/644 - (35%)
• Gaps: 185/644 - (28%)

  Fly    12 LLLLFL--LSTSLHAEISHLPMASNRIILDSTELLQNPLIQDAGVPAAR---------ATPLPPQ 65
            |||||.  |.|..|.    :|| |..|:.::||    .:|..||..:.:         |:|....
 Worm     5 LLLLFTIQLCTPFHV----VPM-SYSILSENTE----SVIDLAGKVSEKRFYLHITNEASPFFMY 60

  Fly    66 KCP----------SLQRYRKMLKDFDDLEDLYVDVPVHIALAERQRKRFVLNLNDSTPLTIRFSA 120
            ..|          ::.:...|.::||.:.|:      ..:|.|.::.:.:...:|...:|. |:.
 Worm    61 VTPCGAAVHWQLFTMDKDISMSEEFDTISDM------SNSLEESEKFKLIAGEDDKKRMTF-FAH 118

  Fly   121 PVGRKMYYNQTGNPLRPAAVAPGPGVAVGSLVLPCALR--GQYDLFVLARHSGALKVDALAEHPQ 183
            .:.:|:..     .:|.|:.:   ..:|.....|...|  .||...                  .
 Worm   119 SLPKKVIL-----VVRAASTS---SASVRIFFTPSLFRLEDQYPPL------------------P 157

  Fly   184 HDWPLLNATHRIAIRTQNRVRKREMIVKW---------ERSKFDFHVMHYCLVIQRLSMDTPRMI 239
            ||..|  ||:.|:..|.:|..:...::.|         |..::     ..|.::.|...:
 Worm   158 HDTRL--ATNIISESTYSRRDEVSTLITWKISPQVRNAEPGRY-----RICTIVSRRDPE----- 210

  Fly   240 FTNFCQAVSAYTDQQPMTPSCAAGGPLEGIWGAPPQRERRLNPRQNVHIVCTGKRRQQLLRRLLP 304
            |...|.    :.::...|..|.                    |:.|..:|....||.:
 Worm   211 FAGMCD----HVEEGVETVKCV--------------------PQTNNTVVIGSLRRDR------- 244

  Fly   305 RSSYHLDLF------GIHQGRQNLTLRLASSQV---------NFNRTQ----PLALKQQALMQLK 350
              :|.:.:|      |.....:..|::  :|:|         |..|.|    |..|....|.|::
 Worm   245 --TYFVTVFVRDHKRGTSSAYEVQTIQ--TSEVVTHRRKVTRNVPRKQKKSAPRVLSNGQLEQVE 305

  Fly   351 IGGQHGKQV----YSFKVPQTTRQLGEPFMRHLLIPCSGSEIRVKLLRQRSEVGKTEAF-----Y 406
            :..:.|..|    :...:|:......:..|  |::......:|:.|.|....:.:::||     :
 Worm   306 LEPKKGTFVNLKFFVNSLPEGAENNTQSAM--LIVHACDGLVRINLFRNGKILKRSDAFSGFRRF 368

  Fly   407 SPTYIRQKGVLPGERYLMRFEPSNDDEALRAQKVMVALSSEALFRDLPELPQNTTVFNVRTRCSR 471
            ..|.||.     |.   :||:..||||.  .:.:.|..|::......|.||.:|:|..|...||.
 Worm   369 VVTNIRS-----GH---LRFQIVNDDET--PKTIRVWASTDLTTSPYPNLPDDTSVKIVGRSCSS 423

  Fly   472 ATIAWNGSPDERELSYCIIVFNLPQRNRSVVDF--------TNYCMDFVPKRVMQYRYFEWMTCR 528
            |:|.|..:.|. .:.||:      .|.|...:|        .|.|...:...|:...|....|..
 Worm   424 ASIQWIRAHDS-HVKYCV------YRRREHSNFLEHLVSLADNLCEGGLSSSVLVGCYTHSPTSS 481

  Fly   529 ERQQSPDNIETETILNLMPGSSYLVYVTANLSMGKP----LPYQALTLHMASQCLDGSH 583
            | ..:...||| ||..|:|.|:|.:.:.|. .:.:|    ||::.:.:.....|  |.|
 Worm   482 E-DDAQSLIET-TIGGLLPASTYRLDLLAT-PLDRPNAQALPFRTVWVRTNRFC--GVH 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nord	NP_611900.1	NDNF	208..333	CDD:462981	19/148 (13%)
		NDNF_C	418..568	CDD:466079	45/161 (28%)
ndnf-1	NP_500282.2	NDNF	181..270	CDD:462981	17/133 (13%)
		NDNF_C	358..532	CDD:466079	50/193 (26%)