Protein Alignment Ir60a and Ir75b

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 598
• Identity: 108/598 - (18%)
• Similarity: 205/598 - (34%)
• Gaps: 174/598 - (29%)

  Fly   176 LFHNATCRNRPLGVASNIFKD----LMEM-----FYVHRVALLYANSTMNYNLL----------- 220
            |.||..    .|||..:|..|    :::|     |:.||...|..:.:||:::|
  Fly    58 LNHNIL----KLGVFLDINCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNFSVLESHFKEAQIFV 118

  Fly   221 -------VNDYYSNVNCRILNVQSVGQCHDGKL----------YPNNAVVKASMQDYVSGFSPRN 268
                   .:|.:|. |..:.:|.:.|:...|:|          ...|..|:..:.:..:..:.::
  Fly   119 DADVTYVTHDPFSK-NFLLYDVYNKGRQLGGELNITADREIFCNKTNCRVERYLSELYTRSALQH 182

  Fly   269 CTFFACSSISAPFVEADCILGLEMR-ILGFM--KNRLKFDVNQTCSLESRGEM------------ 318
            ...|...::.|..|.....|.:.:: |..||  |.|::.|.......::|..:
  Fly   183 RKSFTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIF 247

  Fly   319 -----DGPANWTGLLGKVQNNECDFVFGGYYPDNEVADHFWGSD--TYLQDAHTWYI--KMADRR 374
                 ||.|. .|::|.:..::.|..         :|...:..|  .:||....:.:  ::...|
  Fly   248 RDRWSDGNAT-GGMIGDLILDKADLA---------IAPFIYSFDRALFLQPITKFSVFREICMFR 302

  Fly   375 PAWQALVGI--------FEAYTWIGFILILIIS-WLFWFTLVMILPEPKYYQQLSLTA------- 423
            .......|:        |....|:.|.|:|::: .|.|.|  .||...|.::...||:
  Fly   303 NPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVT--FILERRKQWKPSLLTSCLLSFGA 365

  Fly   424 --INALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTEVV 486
              |....:|        |.....|:.|.||.:....:...|||.:::..........:..|.::.
  Fly   366 GCIQGAWLT--------PRSMGGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLA 422

  Fly   487 AAGIPFG--------------GHEESRDWF--------ENDDDMWI-----------------FN 512
            .:.:..|              ...:.||.:        .:.|.:||                 ..
  Fly   423 DSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEGFVYIT 487

  Fly   513 GYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLF 577
            |.....||:  .|:..|   .|.|.|:      :.||.|..:........||...::|     |.
  Fly   488 GVATGYEFV--RKHFLA---HQICELN------EIPLRDASHTHTVLAKRSPYAELIK-----LS 536

  Fly   578 EMNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWA 642
            |:.     |.:.|:      .|::..:::.  .|:........:.:..|: ..|.||:::|:...
  Fly   537 ELR-----MLETGV------HFKHERSWME--TKLHCYQHNHTVAVGLEY-AAPLFIILLGAIIL 587

  Fly   643 ALTFIG-ELIIHR 654
            .:..:| |:|.||
  Fly   588 CMGILGLEVIWHR 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	8/57 (14%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	10/74 (14%)
		Lig_chan	343..584	CDD:459656	46/278 (17%)