DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir60a and gria1a

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_991161.1	Gene:	gria1a / 798689	ZFINID:	ZDB-GENE-020125-1	Length:	914	Species:	Danio rerio

Alignment Length:	148	Identity:	28/148 - (18%)
Similarity:	55/148 - (37%)	Gaps:	46/148 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 LQDAHTWYIKMADRRPAWQ-ALVGIFEAYTWIGFILILIISWLFWFTLVMILPEPKYYQQLSLTA 423
            :::::.:.|::   ||..| ||||:.|.|.|..|:                      |...|.:.
Zfish   114 MENSNQFVIQL---RPELQDALVGVIEHYRWSKFV----------------------YMYSSDSG 153

  Fly   424 INALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQD-----PGYL---HQLD 480
            ::.|...:..|.:...:            :..:||.....:..:..|||     .|.:   .:|:
Zfish   154 LSVLQKVLDTAAEHNWL------------VTSVNVETMTEASFLKVFQDLDKKKEGQIIIDCELE 206

  Fly   481 ELTEVVAAGIPFGGHEES 498
            .||.::...|..|.:.:|
Zfish   207 RLTSILKKIIELGKNVKS 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
gria1a	NP_991161.1	Periplasmic_Binding_Protein_Type_1	26..387	CDD:299141	28/148 (19%)
		ANF_receptor	36..369	CDD:279440	28/148 (19%)
		PBP2_iGluR_AMPA_GluR1	404..806	CDD:270447
		Lig_chan	536..836	CDD:278489
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591477
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830