Protein Alignment Ir60a and grid1b

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_009304811.1
• Gene: grid1b / 557511
• ZFINID: ZDB-GENE-121214-84
• Length: 1048
• Species: Danio rerio
• Alignment Length: 756
• Identity: 147/756 - (19%)
• Similarity: 254/756 - (33%)
• Gaps: 222/756 - (29%)

  Fly    25 VNLSNETANTVIFMLPEKDLGP--------DVWK-AGVGCLDSFAQIFFFRNPKERFTRAYNLML 80
            |.::.|.::|.|..|....||.        .:|: :.|.|:         ||
Zfish   256 VFVNEEISDTEILELAHSSLGRMTVVRQIFPLWRDSSVSCM---------RN------------- 298

  Fly    81 VHAFHLSSPADQIQEGFSKLINEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYVI 145
              :..:||.....|||:.:.:.  |:|                             |.|.|:.::
Zfish   299 --SHRISSLLCDPQEGYLQSLE--VSN-----------------------------LYLYDSVLM 330

  Fly   146 VVDSVDRLKELMKKKIVEMRS----------WNPGARFLVLFHNATCRNRPLGVASNIFKDLMEM 200
            :.::..|  :|..:|...|.|          ||.|...|....    :.|..|:..  ..|.||.
Zfish   331 LANAFYR--KLEDRKWHSMASLNCIRKSTKPWNGGWSMLETIQ----KGRITGLTG--IMDFMEN 387

  Fly   201 FYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQSVGQCHDGKLYPNNAVVKASMQDYVSGFS 265
                     .:||.:.:.:|...:.......|..:.:....|.    .|.::.::.:::.:.|.:
Zfish   388 ---------GSNSHVQFEILGTSFSETFGKDIKRLATWDSVHG----LNGSLKESRIENGMQGVT 439

  Fly   266 PRNCTFFACSSISAPFV-EADCILGLEMRILGFMKNRL---------KFDVNQTCSLESRGEMDG 320
            .:..|.     :..||| .|:.|||...|..||..:.|         |:|:.|....:...::..
Zfish   440 VKVVTL-----LEDPFVMVAENILGQPKRYKGFSIDVLEALAKILGFKYDIYQVADSKYGSQLSN 499

  Fly   321 PANWTGLLGKVQNNECDFVFGG--YYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQ----A 379
             .:|.|::|::.|...|.....  ..|:.|....|  |..|:.    :.:.:..|:|..:    :
Zfish   500 -GSWNGMIGELINKRADLAVSAITITPERENVVDF--SKRYMD----YSVGILHRKPEEKINIFS 557

  Fly   380 LVGIFEAYTW--IGFILILIISWLFWFTLVMIL-----PEPKYYQQLSLTAINALAVTISIAVQE 437
            |...|:...|  |...:.::...:|..|.:.:|     |...:...:|.:..:|:.:.....||:
Zfish   558 LFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHASSMSNSLHSAIWIVYGAFVQQ 622

  Fly   438 -----------RPICETTRLF-FMALTLYGLNVVATYT-SKM---IATFQDPGYLHQLDELTEVV 486
                       |.:..:..|| .:..:.|..|:.|..| |:|   |.||||  ...|:|
Zfish   623 GGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNTIRTFQD--LARQMD------ 679

  Fly   487 AAGIPFGGHEESR--DWF--------ENDD---DMWIFNGYNISPEF--IPQSKNLEAVKWGQRC 536
               ..:|...:|.  |:|        |.|.   ::|.....|...:|  ...|:.:...|.|...
Zfish   680 ---FAYGTVRDSAVYDYFKAKGTNPLEQDSTYAELWRTISKNNGQDFSVSSPSEGIRKAKKGPYA 741

  Fly   537 ILSNRMYTMQSPLAD---VIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKI--- 595
            .|.:......:.|.|   .|....|::.|....:.|:.|.|:           ||: |.|||
Zfish   742 FLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQHGSPY-----------RDL-ISQKILEL 794

  Fly   596 ----DADF-------RYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGE 649
                |.|.       |.....||..:..:|.    ...|......|.|.||..|...|.|....|
Zfish   795 QEKGDLDVLKQKWWPRTGRCDLNSHSNAQPD----GRSLKLHSFAGVFCILAAGLLLACLVAALE 855

  Fly   650 LIIHRWRTQLVSTSEQQDRRSDKRRRRRRRRKPEKDNRWQR 690
            :    |             .:..|.|:.:.::..||.|..|
Zfish   856 M----W-------------WNSNRCRQEQPKEVTKDYRLAR 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grid1b	XP_009304811.1	PBP1_iGluR_delta_1	25..426	CDD:380615	42/245 (17%)
		Periplasmic_Binding_Protein_Type_2	437..809	CDD:473866	85/406 (21%)