Protein Alignment Ir60a and grik4

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 652
• Identity: 130/652 - (19%)
• Similarity: 220/652 - (33%)
• Gaps: 203/652 - (31%)

  Fly   138 ILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVLFHNATCRNRPLGVASNIFKDLMEMFY 202
            :|.|....||.:|..|.          ||.|.||..|      :|:      :|.|::
Zfish   307 LLFDAVHTVVAAVQELN----------RSQNVGATQL------SCK------SSKIWE------- 342

  Fly   203 VHRVALLYANSTMNYNLLV-------------NDYYSNVNCRIL-----NVQSVGQCHDGK-LYP 248
                   :..|.|||..:|             ....||...||:     .::.:||.|..: |..
Zfish   343 -------HGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALRIMQNSRDGLRQIGQWHSEQGLSM 400

  Fly   249 NNAVVKASMQDYVSGFSPRNCTFFACSSISAPFV---------------EADCILGLEMRILGFM 298
            ...:...::.|.:.     |.|....:.:..|:|               |..|:     .:|..:
Zfish   401 ERKLPSLNVTDTLF-----NTTLTITTILENPYVMLRANHQELEGNDRYEGFCV-----DMLKEL 455

  Fly   299 KNRLKFDVNQTCSLESRGEMDGP-AN--WTGLLGKVQNNECDFVFGG--YYPDNEVADHFWGSDT 358
            .:.|||  .....|...|....| ||  |||::|::.:.:.|.....  ...:.|....|  |..
Zfish   456 ADILKF--KYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDF--SKP 516

  Fly   359 YLQ-DAHTWYIKMADRRPAWQALVGIFEAYTWIGFILILIIS---------------WL------ 401
            ::. .....|.....|||.:.:.:..|....|: |:|:..::               |.
Zfish   517 FMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWL-FMLLAYLAVSCVLFLVARLTPYEWYNPHPCL 580

  Fly   402 ----------------FWFTLVMILPEPKYYQQLSLTAINALAVTISIAVQERPICETTRLFFMA 450
                            |||      |...:.||.|..|..||:......|            :.|
Zfish   581 KGRCSLLINQYSLGNSFWF------PVGGFMQQGSTIAPRALSTRCVSGV------------WWA 627

  Fly   451 LTLYGLNVVATYTSKMIA-----TFQDPGYLHQLDELTEVVAA--GIPFGGHEESRDWFEND--- 505
            .||.   ::::||:.:.|     ..:.|  :..:|:|.:..|.  |...||  .:..:|:|.
Zfish   628 FTLI---IISSYTANLAAFLTVQRMEVP--IESVDDLADQTAIEYGTMHGG--STMTFFQNSRYQ 685

  Fly   506 --DDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMI 568
              ..||.|. |:..|....:|.. |.:   .|.:.||..|.::|.:.: .|...|...:....::
Zfish   686 TYQRMWNFM-YSKQPSVFVKSTE-EGI---ARVLNSNYAYLLESTMNE-YYRQRNCNLTQIGGLL 744

  Fly   569 MKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQF----------PETAIVL 623
            ...|:.....:.|:.|...|:.|.:..:.         ||:..::.::          ...|..|
Zfish   745 DTKGYGIGMPLGSVYRDEFDLAILRLQEE---------NRLEILKRKWWDGGKCPKEEDHRAKGL 800

  Fly   624 TTEHLKGPFFILVVGSC----WAALTFIGELIIHRWRTQLVSTSEQQDRR-------SDKRRRRR 677
            ..|::.|.|.:||.|..    .|.|.|:. ::.|...|:| |..|:..|.       .|..:.||
Zfish   801 GMENIGGIFVVLVCGLLVAIFMAVLEFVW-MLRHTPGTEL-SVCEEMLRELQGIVLCQDSLQLRR 863

  Fly   678 RR 679
            ||
Zfish   864 RR 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	28/129 (22%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	77/409 (19%)