Protein Alignment Ir60a and grik2

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001410875.1
• Gene: grik2 / 556013
• ZFINID: ZDB-GENE-080414-1
• Length: 908
• Species: Danio rerio
• Alignment Length: 686
• Identity: 119/686 - (17%)
• Similarity: 238/686 - (34%)
• Gaps: 175/686 - (25%)

  Fly    86 LSSPADQIQEGFSKLINEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYVIVVDSV 150
            |::...|:.....|...|.:..|..||.            .:.:|.......::.|...:|..:|
Zfish   282 LNTENSQVSSIIEKWSMERLQAPPKPDS------------GLLDGFMTTDAALMYDAVHVVAVAV 334

  Fly   151 DRLKELMKKKIV--EMRSWNPGARFLVLFHNATCRNRPLGVASNIFKDLMEMFYVHRVALLYANS 213
            .:..::....:.  ..:.|..|.||:.|...|                       |...|   ..
Zfish   335 QQSPQITVSSLQCNRHKPWRFGNRFMTLIKEA-----------------------HWDGL---TG 373

  Fly   214 TMNYNLLVNDYYSNVNCRILNVQSVGQCHDGKLYP--------NNAVVKASMQDYVSGFSPRNCT 270
            .:|:| ..|...::.:..:::::..|....|...|        |.....|::.|.:|     |.:
Zfish   374 RINFN-RTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTENQKGKTANVTDSLS-----NRS 432

  Fly   271 FFACSSISAPFV---------------EADCI-LGLEM-RILGF-MKNRLKFDVNQTCSLESRGE 317
            ....:.:..|:|               |..|: |..|: .|||| .:.||..|.......||.|:
Zfish   433 LVVSTILEEPYVMFKKSDKPLYGNDRFEGYCVDLLRELAAILGFGYELRLVEDGRYGAQDESSGQ 497

  Fly   318 MDGPANWTGLLGKVQNNECDFVFGGY---YPDNEVADHFWGSDTYLQDAHTWYIKMADRRP---- 375
                  |.|::.::.:::.|......   |...:|.|       :.:...|..|.:..|:|
Zfish   498 ------WNGMVRELMDHKADLAVAPLAITYVREKVID-------FSKPFMTLGISILYRKPNGTN 549

  Fly   376 -------------AWQALVGIFEAYTWIGFILILI--ISWLFWFTLVMILPEPKYYQQLSLTAIN 425
                         .|   :.|..||..:..:|.:|  .|...|:......|:....:. :.|.:|
Zfish   550 PGVFSFLNPLSPDIW---MYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVEN-NFTLLN 610

  Fly   426 ALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQDPGYLHQLDE 481
            :....:...:|:    .|...:||:.......:.|.::::||:.:.|     ..:.|  :...|:
Zfish   611 SFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESP--IDSADD 673

  Fly   482 LTEVVAAGIPFGGHEE--SRDWFEND-----DDMWIFNGYNISPEFIPQSKN---LEAVKWG-QR 535
            |.:  ...|.:|..|:  :..:|:..     |.||         ||:...::   :::::.| :|
Zfish   674 LAK--QTKIEYGVVEDGSTMTFFKKTKISTYDKMW---------EFMSSRRHSVMVKSIEEGIER 727

  Fly   536 CILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKA-------GFPFLFEMNSIIRLMRDVGIFQ 593
            .:.|:..:.|:|...:.:.....|:......:..||       |.|:..::...|..:::.|...
Zfish   728 VLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKAYGVGTPMGSPYRDKITIAILQLQEEGKLH 792

  Fly   594 KIDADFRYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWRTQ 658
            .:...:...|......||       .|..|..:::.|.|.:|..|...:....:||.:...
Zfish   793 MMKEKWWRGNGCPEEENK-------EASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKS---- 846

  Fly   659 LVSTSEQQDRRS------DKRR-----RRRRRRKPE 683
              ..:.|.::||      |:.|     :||.:.||:
Zfish   847 --KQNAQLEKRSFCSAMVDELRVSLKCQRRLKHKPQ 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grik2	NP_001410875.1	PBP1_iGluR_Kainate	37..414	CDD:380605	25/170 (15%)
		Periplasmic_Binding_Protein_Type_2	430..800	CDD:473866	70/399 (18%)