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Protein Alignment Ir60a and Grik2

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	769	Identity:	145/769 - (18%)
Similarity:	260/769 - (33%)	Gaps:	227/769 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VNLSN----ETANTVIFMLPEKDLGPDVW---------KAGVGCLDSFAQIFFFRNPKERFTRAY 76
            ||::.    .|.||.:..:.||      |         |...|.||.|..           |.|
  Rat   274 VNMTGFRILNTENTQVSSIIEK------WSMERLQAPPKPDSGLLDGFMT-----------TDA- 320

  Fly    77 NLMLVHAFHLSSPADQIQEGFSKLINEAVTNPGPPDREELFQMRVAS--------------DYNI 127
             .::..|.|:.|.|  :|:.....::....|...|.|   |..|..|              .:|.
  Rat   321 -ALMYDAVHVVSVA--VQQFPQMTVSSLQCNRHKPWR---FGTRFMSLIKEAHWEGLTGRITFNK 379

  Fly   128 TNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVLFHNATCRNRPLGVASN 192
            |||.....:|           .|..|||...:||   .:|:|.:..     |.|...:  |..:|
  Rat   380 TNGLRTDFDL-----------DVISLKEEGLEKI---GTWDPASGL-----NMTESQK--GKPAN 423

  Fly   193 IFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQSVGQCHDGKLYPNNAVVKASM 257
            |...|             :|.::....::.:.|      :|..:|     |..||.|
  Rat   424 ITDSL-------------SNRSLIVTTILEEPY------VLFKKS-----DKPLYGN-------- 456

  Fly   258 QDYVSGFSPRNCTFFACSSISAPFVEADCILGL--EMRILGFMKNRLKFDVNQTCSLESRGEMDG 320
             |...|:         |..:   ..|...|||.  |:|::...|...:.|||
  Rat   457 -DRFEGY---------CIDL---LRELSTILGFTYEIRLVEDGKYGAQDDVN------------- 495

  Fly   321 PANWTGLLGKVQNNECDFVFGGY---YPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVG 382
             ..|.|::.::.:::.|......   |...:|.|       :.:...|..|.:..|:|. ....|
  Rat   496 -GQWNGMVRELIDHKADLAVAPLAITYVREKVID-------FSKPFMTLGISILYRKPN-GTNPG 551

  Fly   383 IFEAYT------W-------IGFILILIISWLF----WFTLVMILPEPKYYQQLSLTAINALAVT 430
            :|....      |       :|...:|.:...|    |:......|:....:. :.|.:|:....
  Rat   552 VFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVEN-NFTLLNSFWFG 615

  Fly   431 ISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQDPGYLHQLDELTEVV 486
            :...:::    .|...:||:.......:.|.::::||:.:.|     ..:.|  :...|:|.:
  Rat   616 VGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESP--IDSADDLAK-- 676

  Fly   487 AAGIPFGGHEE--SRDWFEND-----DDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYT 544
            ...|.:|..|:  :..:|:..     |.||.|  .:...:.:....|.|.:   ||.:.|:..:.
  Rat   677 QTKIEYGAVEDGATMTFFKKSKISTYDKMWAF--MSSRRQSVLVKSNEEGI---QRVLTSDYAFL 736

  Fly   545 MQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNTYLNRI 609
            |:|...:.:.....|: :....:|...|:.....|.|..|....:.|.|..:.         .::
  Rat   737 MESTTIEFVTQRNCNL-TQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEE---------GKL 791

  Fly   610 NKMRPQF------PE----TAIVLTTEHLKGPFFILVVGSCWAALTFIGELII-HRWRTQLVSTS 663
            :.|:.::      ||    .|..|..:::.|.|.:|..|...:....:||.:. .:...||...|
  Rat   792 HMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRS 856

  Fly   664 ----EQQDRRSDKRRRRRRRRKPEKDNRWQRQVQVAPVVRFTPVKRRKVFQGQT 713
                ..::.|...:.:||.:.||:           |||:    ||..:|....|
  Rat   857 FCSAMVEELRMSLKCQRRLKHKPQ-----------APVI----VKTEEVINMHT 895

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.